Sökning: "Non insulin dependent diabetes"

Visar resultat 11 - 15 av 77 avhandlingar innehållade orden Non insulin dependent diabetes.

1. 11. Secondary drug failure in non insulin dependent diabetes : on causes and aspects of treatment

   Författare :Per Clauson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Non insulin dependent diabetes; treatment failure; insulin; sulphonylurea; insulin-like growth factor-I; insulin-like growth factor bindingprotein-1; insulin secretion; insulin sensitivity; insulin absorption.;

   Sammanfattning : Non Insulin Dependent Diabetes (NIDDM) represents a major health problem with increased risk of atherosclerotic disease and early death. The grave consequences of NIDDM are partly due to inadequate and insufficient treatment. The purpose of the present study was to study the causes of treatment failure and evaluate new strategies of treatment. LÄS MER

3. 12. Heart Disease in Early type 2 Diabetes

   Författare :Martin Magnusson; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes; Natriuretic peptides; Medicine human and vertebrates ; Medicin människa och djur ; Endokrinologi; diabetology; secreting systems; sekretion; Endocrinology; Heart Disease; diabetologi; Cardiovascular system; Kardiovaskulära systemet;

   Sammanfattning : The steadily increasing prevalence of diabetes constitutes a major health problem. By the year 2025, the prevalence of diabetes is estimated to be as high as 5.4 %. LÄS MER

4. 13. Diabetes in Young Adults : Remission, β-cell function and markers of inflammation

   Författare :Anna Schölin; Elisabeth Björk; Anders Karlsson; Jan Åman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; type 1 diabetes; young adults; remission; β-cell function; islet antibodies; gender; CRP; Invärtesmedicin; Internal medicine; Invärtesmedicin; Internal Medicine; invärtesmedicin;

   Sammanfattning : Type 1 diabetes is caused by immuno-mediated β-cell destruction leading to insulin deficiency and hyperglycaemia. The decline in β-cell function and the clinical course after diagnosis vary. Whether the process of destruction of the β-cells is associated with markers of a non-specific inflammatory response is unknown. LÄS MER

5. 14. The regulation of muscle interstitial insulin, nutrients and blood flow in insulin resistant models. An investigation using the euglycemic insulin clamp and microdialysis techniques

   Författare :Maria Niklasson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin resistance; skeletal muscle; glucose uptake; transcapillary transport; interstitial fluid; euglycemic insulinclamp; microdialysis; blood flow; vasodilation;

   Sammanfattning : Insulin resistance, mainly located to the skeletal muscle tissue, is one prominent feature in thedevelopment of non insulin-dependent diabetes mellitus (NIDDM) and further, associated withcardiovascular diseases. In this context the importance of blood flow for insulin sensitivity has beensuggested by regulating the delivery of insulin and nutrients to the target cells. LÄS MER

7. 15. Anomalies in humoral immunity in the NOD mouse : contribution to the progression of type 1 diabetes

   Författare :Radha Thyagarajan; Kristina Lejon; Per-Arne Oldenborg; Susanna Cardell; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; NOD mouse; B cells; IgE; TACI; BAFF; immunologi; Immunology;

   Sammanfattning : The non-obese diabetic (NOD) mouse is widely used model Type 1 diabetes (T1D), a chronic inflammatory disease characterized by destruction of the insulin producing β cells in the islets of Langerhans by immune cells. The classical symptoms include increased glucose levels in urine and blood, frequent urination and enhanced thirst. LÄS MER