Sökning: "Non insulin dependent diabetes"

Visar resultat 1 - 5 av 76 avhandlingar innehållade orden Non insulin dependent diabetes.

  1. 1. Ett år med diabetes : beskrivning av ett förlopp samt analys av faktorer som stött eller hindrat ett framgångsrikt behandlingsresultat

    Författare :Birgitta S. Eriksson; Stockholms universitet; []
    Nyckelord :SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; SAMHÄLLSVETENSKAP; MEDICAL AND HEALTH SCIENCES; SOCIAL SCIENCES; Diabetes mellitus; non-insulin-dependent; psychology; Diabetes; Patientupplevelser;

    Sammanfattning : .... LÄS MER

  2. 2. Exocytosis in Type 2 Diabetes- Functional and genetic studies of hormone secretion

    Författare :Sofia A Andersson; Diabetes - öcellsexocytos; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Insulin; Glucagon; Alpha-cells; Beta-cells; Exocytosis; Capacitance; SNARE; SNAP25; Syntaxin1A; Synaptotagmin; Munc-18 Stxbp1 ; SNP; Expression; miRNA;

    Sammanfattning : Type 2 Diabetes (T2D) is characterized by dysregulated beta-and alpha-cell hormone secretion leading to elevated blood glucose levels. Several proteins are crucial in maintaining exocytosis of the hormone-containing granules such as Syntaxin1A (Stx1A), SNAP25, Munc-18 (Stxbp1) and the family of Synaptotagmins (Syts). LÄS MER

  3. 3. Murine insulin-dependent diabetes mellitus : a model for disease development and protection

    Författare :Björn Pilström; Dan Holmberg; Stockholms universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease caused by destruction of the insulin-producing beta cells in the pancreatic Langerhans' islets. This destruction is preceded by an infiltration of mononuclear leukocytes called insulitis. LÄS MER

  4. 4. Secondary drug failure in non insulin dependent diabetes

    Författare :Per Clauson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Non insulin dependent diabetes; treatment failure; insulin; sulphonylurea; insulin-like growth factor-I; insulin-like growth factor bindingprotein-1; insulin secretion; insulin sensitivity; insulin absorption.;

    Sammanfattning : SECONDARY DRUG FAILURE IN NON INSULIN DEPENDENT DIABETESON CAUSES AND ASPECTS OF TREATMENTPer Clauson, MD, Department of Endocrinology and Diabetology, KarolinskaInstitute, Stockholm, Sweden Non Insulin Dependent Diabetes (NIDDM) represents a major healthproblem with increased risk of atherosclerotic disease and early death. Thegrave consequences of NIDDM are partly due to inadequate and insufficienttreatment. LÄS MER

  5. 5. Pharmacokinetics - Effect Relations of Glibenclamide and its Metabolites in Humans

    Författare :Tony S Rydberg; Institutionen för hälsovetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; renal insufficiency.; insulin; glucose; non-insulin dependent; diabetes mellitus; pharmacodynamic modelling; pharmacodynamics; pharmaco-kinetics; HPLC method; Glibenclamide; sulphonylurea; metabolites; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : Glibenclamide (Gb) is the most commonly employed sulphonylurea worldwide for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). There has been uncertainty concerning its pharmacokinetics (PK) and pharmacodynamics (PD). LÄS MER