Sökning: "Nogo-A"

Hittade 2 avhandlingar innehållade ordet Nogo-A.

  1. 1. Towards cell replacement therapy in Parkinson’s disease. Proteoglycans and Nogo-A as modulators of axonal growth in midbrain dopaminergic neurons

    Författare :Zuzanna Kurowska; Neural plasticitet och reparation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LUHMES cells; substantia nigra pars compacta; microarray; heparan sulphate 3-O-sulfotransferase; neurocan; midbrain dopaminergic neurons; grafting; embryonic stem cells; proteoglycans; glycosaminoglycans; Nogo-A; cell replacement therapy; Parkinson’s disease;

    Sammanfattning : Parkinson’s disease (PD) is currently the second most common neurodegenerative disorder (after Alzheimer’s disease). PD is diagnosed on its motor symptoms, which include akinesia, bradykinesia, rigidity, postural imbalance and resting tremor. It is well established that the motor symptoms develop due to lack of dopamine in the striatum. LÄS MER

  3. 2. Spinal cord injury : mechanical and molecular aspects

    Författare :Anna Josephson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Spinal cord; syringomyelia; MRI; fMRI; neurotrophin; Nogo; Nogo receptor; regulation;

    Sammanfattning : Traumatic spinal cord injury leads to full or partial paralysis and loss of sensation below the level of injury. The annual incidence of spinal cord injury in the United States is 3-5 per 100,000 and in Sweden is 1.5-2 per 100,000. This translates to 11,000 new cases of traumatic spinal cord injury in the US and 150 in Sweden each year. LÄS MER