Sökning: "Nitric oxide reduction"

Visar resultat 1 - 5 av 88 avhandlingar innehållade orden Nitric oxide reduction.

  1. 1. Heme-copper oxidases and nitric oxide : Reaction mechanisms and supercomplex formation

    Författare :Ingrid Albertsson; Pia Ädelroth; Alessandro Giuffrè; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Heme-copper oxidase; nitrite reductase; nitric oxide reductase; nitric oxide; supercomplex; Paracoccus denitrificans; denitrification pathway; proton transfer pathway; C-type oxidase; Helicobacter pylori; Biochemistry; biokemi;

    Sammanfattning : In the denitrification process where nitrate is stepwise reduced to nitrogen gas, the toxic molecule nitric oxide (NO) is formed as an intermediate. Nitric oxide is produced by the enzyme cd1 Nitrite reductase (cd1NiR) by reduction of nitrite and is later reduced to nitrous oxide by nitric oxide reductase (cNOR). LÄS MER

  3. 2. Endogenous Nitric Oxide Production and Pulmonary Blood Flow : during different experimental lung conditions

    Författare :Manja Nilsson; Filip Fredén; Kristina Hambraeus-Jonzon; Göran Hedenstierna; Eddie Weitzberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nitric oxide; pulmonary blood flow; endotoxin; nitric oxide inhalation; endothelin; hypercapnia; acidosis; lavage-induced lung injury; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : Nitric oxide (NO) is an important regulator of pulmonary blood flow and attenuates hypoxic pulmonary vasoconstriction (HPV). Nitric oxide is synthesized enzymatically in a number of tissues, including the lungs, and can also be generated from reduction of nitrite during hypoxia and acidosis. LÄS MER

  4. 3. Electron and Proton Transfer in Nitric Oxide Reductase : NO Binding, NO Reduction and no Pumping

    Författare :Peter Lachmann; Pia Ädelroth; Peter Brzezinski; Fahmi Himo; Stockholms universitet; []
    Nyckelord :Flow-Flash; Nitric Oxide Reductase; Heme Copper Oxidase;

    Sammanfattning : Nitric oxide reductase (NOR) from Paracoccus denitrificans catalyzes the two electronreduction of NO to N2O (2NO + 2H+ + 2e- → N2O + H2O) as part of the process ofdenitrification, the step-wise reduction of nitrate to dinitogen. The NOR-catalyzedreaction is central in the nitrogen cycle, since in this step the N=N double bond isformed. LÄS MER

  5. 4. The hyperosmolar airway : Mechanisms of reduced response to nitric oxide

    Författare :Josephine Hjoberg; Uppsala universitet; []
    Nyckelord :Medical sciences; 8-Br-cyclic GMP; airway epithelium; airway reactivity; airway smooth muscle; amiloride; epithelium derived relaxing factor; furosemide; hyperosmolarity; hypertonic saline; nitric oxide; SNAP; sodium chloride; sodium nitroprusside; superoxide; tracheal perfusion; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Physiology; klinisk fysiologi;

    Sammanfattning : Inhaled nitric oxide (NO) relaxes smooth muscle of the airways and of pulmonary blood vessels and is used to treat lung diseases where the pulmonary vessels are constricted. NO has also been tested as a bronchodilator in asthmatic patients. LÄS MER

  7. 5. Nitric Oxide Regulation during Anti-tumor Immunotherapy

    Författare :Wiaam Badn; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serology; Immunology; Medicin människa och djur ; immunotherapy; Medicine human and vertebrates ; immunosuppression; PGE2; Nitric oxide; serologi;

    Sammanfattning : During tumor progression a strong immunosuppression is developed and is believed to be the major reason why immunotherapy fails. This suppression is induced in response to factors produced from tumor cells, but can also be induced after immunotherapy. LÄS MER