Sökning: "Nina Rökaeus"

Hittade 1 avhandling innehållade orden Nina Rökaeus.

1. 1. Pharmacological targeting of mutant p53 family members

   Författare :Nina Rökaeus; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The tumor suppressor p53 serves as a guardian of the genome and functions mainly as a transcription factor. In response to various stress signals p53 binds to specific DNA sequence motifs and regulates transcription of a large group of target genes involved in cellular processes such as cell cycle arrest, senescence and apoptosis. LÄS MER