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  1. 1. Ghrelin and CART. Two new islet peptides. Expression, regulation and function

    Författare :Nils Wierup; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; diabetology; histology; endocrinology; islets; CART; Ghrelin cells; insulin secretion; type-2 diabetes; Ghrelin;

    Sammanfattning : Until recently, the islets of Langerhans were thought to harbour four main cell types characterised with respect to principal hormone product. Here we show that the novel hormone ghrelin is expressed in a fifth islet cell type, the islet ghrelin cell, in humans and rodents. LÄS MER

  2. 2. Clinical and immunohistochemical studies of small bowel carcinoid tumours

    Författare :Kalle Landerholm; Johannes Järhult; Nils Wierup; Sture Falkmer; Roland Andersson; Bo Wängberg; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Small bowel carcinoid tumours arising from enterochromaffin cells in the jejunum and ileum are neuroendocrine tumours (NETs) characterized by secretion of serotonin, tachykinins and other bioactive substances. These substances may lead to the typical carcinoid syndrome as well as pronounced fibrosis locally and in the heart. LÄS MER