Sökning: "Nil Dizdar"

Hittade 5 avhandlingar innehållade orden Nil Dizdar.

  1. 1. Microdialysis as a Tool in Studies of L-Dopa and Metabolites in Malignant Melanoma and Parkinson’s Disease

    Författare :Nil Dizdar (Dizdar Segrell); Bertil Kågedal; Jan-Edvin Olsson; Christer Hansson; Linköpings universitet; []
    Nyckelord :Microdialysis; L-Dopa; Malignant Melanoma; Parkinson s Disease; in vivo; MEDICINE; MEDICIN;

    Sammanfattning : A model with human melanoma xenografts transplanted to athymic mice has been adopted for in vivo studies of 5-S-cysteinyldopa (an intermediate pigment metabolite), glutathione, and cysteine. L-Dopa is an intermediate metabolite in pigment formation and is also important in the treatment of Parkinson's disease, and therefore 1 have also studied the pharmacokinetics of this compound. LÄS MER

  3. 2. Biochemical and pharmacokinetic studies in vivo in Parkinson’s disease

    Författare :Peter Zsigmond; Nil Dizdar (Dizdar Segrell); Jan Hillman; Stig Rehncrona; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Parkinson’s disease (PD) is a neurodegenerative disease affecting approximately 25000 people in Sweden. The main cause of the disease is the degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc) projecting to the striatum. LÄS MER

  4. 3. Imaging Studies of Olfaction in Health and Parkinsonism

    Författare :Charalampos Georgiopoulos; Elna-Marie Larsson; Maria Engström; Nil Dizdar; Helene Zachrisson; Asta Kristine Håberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Olfactory loss is a common non-motor symptom of Parkinson’s disease (PD), often preceding the cardinal motor symptoms of the disease. The aim of this thesis was to: (a) evaluate whether olfactory examination can increase diagnostic accuracy, and (b) study the structural and functional neural basis of olfactory dysfunction in PD with different applications of Magnetic Resonance Imaging (MRI). LÄS MER

  5. 4. Self-management support to handle everyday life with Parkinson´s disease

    Författare :Carina Hellqvist; Carina Berterö; Peter Hagell; Märtha Sund-Levander; Nil Dizdar Segrell; Stefan Sävenstedt; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; self-management; everyday life; self-care support; care partners; self-management intervention;

    Sammanfattning : Background: Being diagnosed with Parkinson´s disease (PD) is a life-altering experience. The long-term condition requires continuous adjustments to the everyday life not only of the person affected, but also for care partners. LÄS MER

  7. 5. Levodopa pharmacokinetics -from stomach to brain : A study on patients with Parkinson’s disease

    Författare :Maria Nord; Nil Dizdar; Jonas Lind; Peter Söderkvist; Filip Bergquist; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Parkinson’s disease (PD) is one of the most common neurodegenerative disorders and it is caused by a loss of dopamine (DA) producing neurons in the basal ganglia in the brain. The PD patient suffers from motor symptoms such as tremor, bradykinesia and rigidity and treatment with levodopa (LD), the precursor of DA, has positive effects on these symptoms. LÄS MER