Sökning: "Niklas Bergh"

Hittade 2 avhandlingar innehållade orden Niklas Bergh.

  1. 1. Development of a New Biomechanical ex vivo Perfusion System - Studies on effects of biomechanical and inflammatory stress on hemostatic genes in human vascular endothelium

    Författare :Niklas Bergh; Göteborgs universitet; []
    Nyckelord :ex vivo perfusion system; biomechanical; endothelium; shear stress; tensile stress; pulsatile; TNF-α; JNK; hemostatic genes;

    Sammanfattning : The vascular endothelium is a multifunctional interface constantly exposed to biomechanical forces such as shear and tensile stress. Biomechanical stress is involved in the pathophysiological process of the vessel wall and thus affects vascular remodeling, atherosclerosis and thrombogenesis. LÄS MER

  3. 2. Mineralocorticoid receptor antagonists in heart failure : exploring the gap between guideline-directed medical therapy and real-world practice

    Författare :Anna Jonsson Holmdahl; Krister Lindmark; Helena Norberg; Ellinor Bergdahl; Fredrik Valham; Niklas Bergh; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart failure; Mineralocorticoid receptor antagonists; estimated glomerular filtration rate; hyperkalemia; impaired renal function; worsening renal function; guideline-directed medical therapy; kardiologi; Cardiology;

    Sammanfattning : Heart failure is the possible end-result of a variety of different diseases, where ischemic heart disease and hypertension are the most common causes in high income countries. In Sweden, heart failure has a prevalence of 2% in the adult population and rises to over 10% among people over 70 years of age. The 5-year all-cause mortality is about 50%. LÄS MER