Sökning: "Neurotoxikologi"
Visar resultat 1 - 5 av 33 avhandlingar innehållade ordet Neurotoxikologi.
1. Interleukin 1, tumor necrosis factor α and interleukin 6 in the rat central nervous system : production and effects with particular attention to the fever response
Sammanfattning : .... LÄS MER
2. Astroglial Cells : Role in Neurodegenerative-Inflammatory Processes in the Central Nervous System
Sammanfattning : Inflammatory processes, mediated by the pro-inflammatory cytokines interleukin (IL) -1a/b, tumor necrosis factora(TNFa), IL-6 and excitotoxic actions of glutamate, are proposed to be implicated in neurodegenerative diseases, such as Alzheimer's disease.A neurotoxic fragment ofb-amyloid,bA25-35, was shown to induce a reactive phenotype of primary astrocytes and microglial cells in a time-dependent manner. LÄS MER
3. Galanin : Studies by Modification of the Ligand and the Receptor
Sammanfattning : This thesis is devoted to the deeper understanding of the molecular details of the interaction between the neuropeptide galanin and its target protein, the G-protein coupled 7TM galanin receptor. The enzymatic control of galanin degradation and second messenger systems triggered by galanin receptor activation are also studied. LÄS MER
4. Applications of multi-component condensations and development of polyamine synthesis on solid-phase
Sammanfattning : Solid-phase synthesis of small non-polymeric molecules has become increasingly important as a tool in the development of pharmacologically active compounds. Of particular interest are the syntheses of compounds with low molecular weight, low polarity and a reduced flexibility of the functional groups, i.e. LÄS MER
5. Galanin and neuropeptide Y analogs : receptor-ligand interactions and pharmacology
Sammanfattning : .... LÄS MER
