Sökning: "Neurological disorders"

Visar resultat 21 - 25 av 179 avhandlingar innehållade orden Neurological disorders.

  1. 21. Fluid biomarkers of extracellular matrix remodelling across neurological diseases

    Författare :Karolina Minta; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; biomarker; extracellular matrix; idiopathic normal pressure hydrocephalus; immunoassay; mass spectrometry; radiation-induced brain injury; traumatic brain injury; vascular dementia;

    Sammanfattning : Neurological diseases constitute a major health and socioeconomic issue. Despite an enormous amount of research going on globally, the prevalence and mortality of neurological disorders are still rising. LÄS MER

  3. 22. Cognitive deficits and HIV-associated psychotic disorders in Uganda

    Författare :Noeline Nakasujja; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV AIDS;

    Sammanfattning : Introduction: HIV infection is known to cause neuro-psychiatric disturbances whose prevalence ranges between 74-83%. The prevalence of HIV in patients with psychosis has been found at 18%. Cognitive dysfunction occurs in 37% of HIV individuals with advanced HIV/AIDS even after the initiation of antiretroviral therapy. LÄS MER

  4. 23. Mental Health and Neurobehavioral Function in Young Adult Offspring of Women with a History of Psychosis and Control Offspring

    Författare :Erland Schubert; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychiatry; klinisk psykologi; Psykiatri; psykosomatik; clinical psychology; visual dysfunction; neuropsychological function; neurological abnormality; neurodevelopment; mental disturbance; high-risk; genetic; schizophrenia; affective psychosis; psychosomatics;

    Sammanfattning : Schizophrenia is now generally considered to be a brain disease resulting from disturbed neurodevelopment, mediated by genetic and/or adverse events in utero and/or in early childhood. This process manifests itself in schizophrenia in young adulthood, when the brain completes its maturation. LÄS MER

  5. 24. Proteomic strategies for analysis of cerebrospinal fluid in neurodegenerative disorders

    Författare :Sara Folkesson Hansson; Göteborgs universitet; []
    Nyckelord :Alzheimer?s disease; frontotemporal dementia; cerebrospinal fluid; neurodegeneration; proteomics; mass spectrometry; prefractionation; protein identification; quantification;

    Sammanfattning : ABSTRACT There is a great need for biomarkers to diagnose neurodegenerative disorders, such as the cognitive disorders Alzheimer?s disease (AD) and frontotemporal dementia (FTD). Cerebrospinal fluid (CSF) is in contact with the extracellular fluid of the brain and is consequently a valuable medium for identifying biomarkers for neurological disorders. LÄS MER

  7. 25. Cellular models of human brain disorders from skin to brain

    Författare :Mansoureh Shahsavani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Studying human brain development and disorders is very challenging. In the absence of comparable model organisms, human-related models, and limitations to obtain live cells from the human brain, induced Pluripotent Stem Cell (iPSC) technology, in particular, provided a unique tool to study the disease mechanisms and investigate potential treatments. LÄS MER