Sökning: "Neurokinin"

Visar resultat 11 - 15 av 34 avhandlingar innehållade ordet Neurokinin.

  1. 11. Neuropeptides in temporomandibular joint arthritis

    Författare :Anna Appelgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adjuvant; Arthritis; Calcitonin gene-related peptide; Glucocorticosteroids; Hippocampus; Hyperalgesia; Hypothalamus; Hypothalamo-pituitary-adrenal axis; Intra-articular temperature; Neurokinin A; Neuropeptides; Neuropeptide Y; Nociception; Pain; Pituitary; Pressure pain threshold; Rheumatoid arthritis; Substance P; Synovial fluid; Temporomandibularjoint; Visual analog scale;

    Sammanfattning : Involvement of the peripheral and central nervous systems in the pathophysiology of arthritis has been suggested and neuropeptides are thought to participate in the mediation and modulation of the inflammatory process. The main objective of the clinical studies was to investigate the relationship between the presence of neuropeptides in the synovial fluid of the temporomandibular joint (TMJ) and the stomatognathic symptoms and signs, including the intra-articular temperature (IAT), in patients with TMJ arthritis. LÄS MER

  3. 12. Neuropeptides in bone and joint tissues : alteration in adjuvant arthitis

    Författare :Adlan Mahmoud Elhassan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In this thesis, the localization, distribution and quantification of met-enkephalin (Met-enk), neurokinin-A and somatostatin in normal bone and joint tissues of the rat have been studied. Moreover, concentration alterations of these neuropeptides at the site of inflammation in the arthritic ankle joints as well as the spinal cords were evaluated. LÄS MER

  4. 13. Tachykinergic mechanisms in atopic dermatitis

    Författare :Louise Lönndahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atopic dermatitis (AD) is an often severely itching, chronic, inflammatory skin disorder and may worsen due to stress and anxiety. Tachykinins have been suggested to influence the level of inflammation as well as being involved in pruritus, stress and anxiety. LÄS MER

  5. 14. Effects of Inflammatory Mediators on Pulmonary Airways

    Författare :Ofir Bachar; Klinisk och experimentell allergiforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electric ?eld stimulation; bradykinin; airway; tumor necrosis factor a; Respiratory system; nitric oxide; Andningsorganen; Toll-like receptor; prostaglandin E2; neurotrophin; allergy;

    Sammanfattning : Chronic inflammation is together with excessive contraction of the airways key features of asthma. The aims of the thesis were to analyze the effect of inflammatory mediators on airway smooth muscle, using an in vitro model of cultured murine airways. LÄS MER

  7. 15. Modulation by substance P in the lamprey spinal cord

    Författare :Carolina Thörn Pérez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neuromodulation is a key element for animal adaptation to environmental circumstances. Neuromodulators can alter the output of a physiological system by acting on the motor circuit by transforming intrinsic firing properties and altering synaptic strength. Substance P belongs to the family of tachykinin, which are peptidergic neuromodulators. LÄS MER