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Visar resultat 1 - 5 av 34 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Imaging Anxiety : Neurochemistry in Anxiety Disorders Assessed by Positron Emission Tomography

    Författare :Andreas Frick; Mats Fredrikson; Tomas Furmark; David J Nutt; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Fear; Brain; Serotonin; Neurokinin; Substance P; Psychology; Psykologi;

    Sammanfattning : Anxiety disorders, including social anxiety disorder (SAD) and posttraumatic stress disorder (PTSD) are common and disabling conditions. Largely based on animal and pharmacological studies, both the serotonergic and substance P/neurokinin-1 (SP/NK1) systems have been implicated in their underlying pathology. LÄS MER

  2. 2. Imaging Chronic Pain and Inflammation : Positron Emission Tomography Studies of Whiplash Associated Disorder

    Författare :Clas Linnman; Mats Fredrikson; Tomas Furmark; Israel Liberzon; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Whiplash Associated Disorder; PET; brain; chronic pain; rCBF; neurokinin-1; Substance P; inflammation; D-deprenyl; fear of movement; kinesiophobia; ; Psychology; Psykologi;

    Sammanfattning : This thesis is on chronic neck pain after a rear impact car injury, so called whiplash associated disorder (WAD). Three empirical studies using positron emission tomography (PET) with different radioligands have been performed. LÄS MER

  3. 3. Psychological aspects of patients with psoriasis: Biological and clinical studies

    Författare :Charlotta Remröd; Yrkes- och miljödermatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psoriasis; psychology; Substance P; Neurokinin-1; stress; pruritus; anxiety; depression; personality;

    Sammanfattning : Psychological distress is well known to be associated with psoriasis, both as a disease consequence, and as a causative factor for onset and exacerbations. Psychoneuroimmunological mechanisms have been suggested to be involved in the pathogenesis of psoriasis and have often been shown to be related to psychological distress and pruritus in psoriasis. LÄS MER

  4. 4. Immune regulation of herpes simplex virus type 2 infection: Special emphasis on the transcription factor T-bet

    Författare :Alexandra Svensson; Göteborgs universitet; []
    Nyckelord :HSV-2; T-bet; Substance P; Neurokinin 1; IFN-alfa beta signaling; Polymorphisms;

    Sammanfattning : Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the genital tract mucosa as well as local sensory neurons. It is the most common cause of genital ulcer disease in humans. The infection gives rise to a wide range of symptoms, ranging from severe and painful recurrent episodes of genital herpes to silent infection. LÄS MER

  5. 5. Positron Emission Tomography (PET) Studies in Anxiety Disorders

    Författare :Åsa Michelgård Palmquist; Mats Fredrikson; Lars von Knorring; Hans Ågren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Positron emission tomography; PET; amygdala; fear; anxiety; anxiety disorders; specific phobia; social phobia; posttraumatic stress disorder; PTSD; regional cerebral blood flow; rCBF; substance P; SP; neurokinin 1 receptor; NK1; GR205171; STAI-S; Psychiatry; Psykiatri; Neurobiology; Neurobiologi; Neuroscience; Neurovetenskap; Experimental brain research; Experimentell hjärnforskning; Molecular neurobiology; Molekylär neurobiologi; Radiation biology; Strålningsbiologi; Neurobiology; Neurobiologi; Neurobiology; Neurobiologi;

    Sammanfattning : Anxiety disorders are very common and the primary feature is abnormal or inappropriate anxiety. Fear and anxiety is often mediated by the amygdala, a brain structure rich in substance P (SP) and neurokinin 1 (NK1) receptors. LÄS MER