Sökning: "Neurodegenerativ"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet Neurodegenerativ.

  1. 1. ­­­Visual assessment of perfusion and metabolism in neurodegenerative dementia

    Författare :David Fällmar; Elna-Marie Larsson; Lena Kilander; Mark Lubberink; Ian Law; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dementia; Neurodegenerative; Brain imaging; Diagnostics; Neuroradiology; Neuroimaging; Demens; Neurodegenerativ; Hjärnavbildning; diagnostik; Neuroradiologi; Neuroimaging; Radiology; Radiologi;

    Sammanfattning : A worldwide demographic shift is currently occurring, with rapidly increasing numbers of elderly individuals. Since the incidence of neurodegenerative disease generally increases with age, this entails an increase in dementia prevalence. LÄS MER

  3. 2. A peripheral immune response in Huntington's disease and delineation of its importance in disease pathology

    Författare :Anna Magnusson-Lind; Biomarkörer vid hjärnsjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington s disease; peripheral symptoms; immune response; muscle atrophy; cytokines; gene expression; JAK STAT; NFkB; IL-6; TNF-alpha;

    Sammanfattning : Huntington’s disease (HD) is a fatal, hereditary disease for which there is no cure. It is caused by a mutation in a gene called huntingtin. HD is a so-called neurodegenerative disease, where there is a loss of neurons in areas of the brain that control body movements. This results in uncontrolled dance-like movements (chorea). LÄS MER

  4. 3. Quantitative MRI Biomarkers of Neurodegeneration in Multiple Sclerosis

    Författare :Michael Platten; Tobias Granberg; Chunliang Wang; Fredrik Piehl; Sara Shams; Mattias Vågberg; KTH; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Machine learning; Multiple sclerosis; Corpus callosum; Neurodegeneration; Medical Technology; Medicinsk teknologi;

    Sammanfattning : Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease that targets myelin in the brain and spinal cord. The corpus callosum connects the cerebral hemispheres and is composed of heavily myelinated axons. LÄS MER

  5. 4. Models and biomarkers of motor and neuropsychiatric complications in Parkinson’s disease

    Författare :Katrine Skovgård; Basala gangliernas patofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease Parkinsonism; Dyskinesia; Drug-Induced; Oscillations; Local field potentials; Impulsive-compulsive behaviours; Dopamine agonists; Animal Models; Pharmacology;

    Sammanfattning : Parkinson's disease (PD) is a neurodegenerative disorder characterised by typicalmotor symptoms that are caused by severe dopamine depletion in the cortico-basalganglia network. Parkinsonian motor symptoms are improved by dopaminergicmedications, the most effective being the dopamine precursor L-DOPA. LÄS MER

  7. 5. Extraocular Muscles in Amyotrophic Lateral Sclerosis

    Författare :Anton Tjust; Fatima Pedrosa Domellöf; Mona Lindström; Thomas Brännström; Eva Hedlund; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; EOM; Satellite cells; innervation; neuromuscular disease; neurodegenerative disease; anatomi; Human Anatomy;

    Sammanfattning : Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease of motor neurons characterized by muscle paralysis and death within 3-5 years of onset. However, due to unknown mechanisms, the extraocular muscles (EOMs) remain remarkably unaffected. LÄS MER