Sökning: "Neurochemistry and Neurotoxicology"

Visar resultat 11 - 15 av 22 avhandlingar innehållade orden Neurochemistry and Neurotoxicology.

  1. 11. Interleukin-1 Receptors and their Ligands

    Författare :David Malinowsky; Gordon W Duff; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : Interleukin-1 (IL-1) is an endogenous mediator of the inflammatory response. IL-1 executes its actions by binding and subsequent activation of the IL-1 receptor (IL-1R) proteins. Among the many systemic effects of IL-1, the fever response was the first to be investigated. LÄS MER

  3. 12. Development of a new class of protecting groups for use in solid phase peptide synthesis

    Författare :Amelie Karlström; James P Tam; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry; Neurokemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : .... LÄS MER

  4. 13. On inflammatory cytokines and β-amyloid peptides in acute and chronic neurodegeneration

    Författare :Roya Tehranian; Gianluigi Forloni; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; Cytokines; Amyloid; Peptides; Nerve degeneration; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Insults to the brain as well as neurodegenerative diseases are known to elicit inflammatory responses. Inflammation in the brain can on one hand initiate processes that are harmful to the injured tissue and exacerbate the damage, leading to neuronal degeneration and glial activation, and on the other hand activate processes that may be necessary for repair mechanisms and regeneration. LÄS MER

  5. 14. Galanin : Studies by Modification of the Ligand and the Receptor

    Författare :Anders Juréus; Claes-Göran Östeson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Other chemistry; Övrig kemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : This thesis is devoted to the deeper understanding of the molecular details of the interaction between the neuropeptide galanin and its target protein, the G-protein coupled 7TM galanin receptor. The enzymatic control of galanin degradation and second messenger systems triggered by galanin receptor activation are also studied. LÄS MER

  7. 15. Cell-penetrating peptides : Uptake, stability and biological activity

    Författare :Tina Holm; Ülo Langel; Roland Brock; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Cell-penetrating peptides (CPPs) have emerged as a group of remarkable delivery vectors for various hydrophilic macromolecules, otherwise excluded from cells due to the protective plasma membrane. Unbiased conclusions regarding e.g. LÄS MER