Sökning: "Neural Precursors"
Visar resultat 1 - 5 av 33 avhandlingar innehållade orden Neural Precursors.
1. Neural Stem Cell Differentiation and Migration
Sammanfattning : Neural stem cells are the precursors of neurons, astrocytes and oligodendrocytes. During neural development, the division of stem cells takes place close to the lumen of the neural tube, after which they migrate to their final positions within the central nervous system (CNS). LÄS MER
2. Generation of cells for cell-replacement therapy: Specification of neural precursors in vivo and in neural stem cell cultures
Sammanfattning : Cell replacement therapy of neurodegenerative disorders aims to substitute the degenerating cells with new functional neurons. Clinical trails with patients suffering from Parkinson’s or Huntington’s disease have generated proof-of-principle results that neural precursors taken from the developing human brain can survive upon grafting to the diseased brain and provide long-lasting symptomatic relief. LÄS MER
3. Neurogenesis and gliogenesis after focal brain ischemia. Modulation by enriched environment and exercise
Sammanfattning : New neurons are formed from dividing neural stem cells in restricted areas in the adult mammalian brain: the dentate gyrus of the hippocampal formation (DG) and the forebrain subventricular zone (SVZ). New glia also form constitutively and seem to be important for neuronal function. LÄS MER
4. On molecular mechanisms of neural differentiation and forebrain development
Sammanfattning : Telencephalic development is an extraordinary complex process where neural structures of highly diverse cell compositions emerge as the result of multiple developmental strategies imposing tight regulation, balance and timing of gene expression. Embryonic telencephalic neural stem cells (NSCs) can form the major cell types found in the telencephalon, and are thus an excellent model for studying transcriptional control of lineage choice mechanisms in CNS development. LÄS MER
5. Fate selection in the neural crest lineage and its regulation
Sammanfattning : The neural crest is a transient embryonic progenitor cell population that generates a diverse array of cell and tissue types, including cartilage, bone, teeth, soft connective and adipose tissues, peripheral sensory and autonomic neurons, myelinating and non-myelinating Schwann cells, melanocytes, cardiac outflow tract, adrenal medulla and other derivatives. Neural crest cells start as neuroepithelial cells forming at the border of neural and non-neural ectoderm in a vertebrate embryo. LÄS MER