Sökning: "Neural Interfaces"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden Neural Interfaces.

  1. 1. Conjugated Polymers for Neural Interfaces : Prospects, possibilities and future challenges

    Författare :Maria Asplund; Hans von Holst; Olle Inganäs; Thomas Stieglitz; KTH; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; MEDICIN OCH HÄLSOVETENSKAP; ENGINEERING AND TECHNOLOGY; ENGINEERING AND TECHNOLOGY; MEDICAL AND HEALTH SCIENCES; neuroprosthetics; conjugated polymers; conducting polymers; PEDOT; functional electrical stimulation; neural electrodes; Medical engineering; Medicinsk teknik; Neuroscience; Neurovetenskap; Functional materials; Funktionella material;

    Sammanfattning : Within the field of neuroprosthetics the possibility to use implanted electrodes for communication with the nervous system is explored. Much effort is put into the material aspects of the electrode implant to increase charge injection capacity, suppress foreign body response and build micro sized electrode arrays allowing close contact with neurons. LÄS MER

  2. 2. Silicon neural interfaces -Design and biomedical aspects-

    Författare :Lars Wallman; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Elektronik och elektroteknik; Electronics and Electrical technology; pn-etch stop; biocompatibility; neural recordings; porous silicon; silicon; neural interface; sieve electrode; General biomedical sciences; Biomedicinska vetenskaper allmänt ;

    Sammanfattning : This thesis covers the development of a silicon neural interface, with focus on silicon sieve electrode fabrication, design, nerve regeneration, signal recording and biocompatibility. A study of how the via hole size and transparency of the perforated sieve membrane influences the nerve regeneration is presented together with a study on soft tissue responses to planar and porous silicon. LÄS MER

  3. 3. Nanowires and Neural interfaces. Biocompatibility in the brain

    Författare :Lina Gällentoft; NanoLund; []
    Nyckelord :neural interface; neurons; BMI; nanowires; tissue responses; rat; biocompatibility; astrocytes; microglia;

    Sammanfattning : Chronic neural interfaces that are able to record or stimulate neurons in the CNS are valuable instruments in use today and they hold great promise for the future both within neuroscience research and in the clinic. However, a major obstacle is that they show a decline in performance over time. LÄS MER

  4. 4. Nanoparticle-based drug delivery systems for neural interfaces - a novel approach for improved biocompatibility

    Författare :Alexander Dontsios Holmkvist; Neurofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Neural interfaces; brain damage injury; Minocycline; Gelatin; Nanoparticles; Drug-delivery systems; Biocompatibility; Tissue responses; immunohistochemistry IHC ; Poly D; L-lactic-co-glycolic acid PLGA ; Hydrophobic ion paring; Emulsification-solvent-diffusion method; Drug release; Microglia activation;

    Sammanfattning : The overall purpose of this thesis was to reduce brain tissue responses around implanted microelectrodes using a pharmacological strategy. One of the main aims was to develop and evaluate drug delivery systems that allow local administration of anti-inflammatory pharmaceutics. LÄS MER

  5. 5. Circuit Design Techniques for Implantable Closed-Loop Neural Interfaces

    Författare :Nikola Ivanisevic; Ana Rusu; Saul Rodriguez; Angel Rodriguez Vazquez; KTH; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Neural interface; ECoG; high-resolution; ADC; recording; delta-sigma modulator; system identification; impedance measurements; Informations- och kommunikationsteknik; Information and Communication Technology;

    Sammanfattning : Implantable neural interfaces are microelectronic systems, which have the potential to enable a wide range of applications, such as diagnosis and treatment of neurological disorders. These applications depend on neural interfaces to accurately record electrical activity from the surface of the brain, referred to as electrocorticography (ECoG), and provide controlled electrical stimulation as feedback. LÄS MER