Sökning: "Neu5Ac"
Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet Neu5Ac.
1. Tailored conjugates of N-acetylneuraminic acid and small molecules that block virus cell attachment and entry
Sammanfattning : Viruses are obligate intracellular parasites, unable to replicate without exploiting machinery andmaterials from host cells. Pandemics of viral diseases have had large impacts on human socieities and are continued threats to global health. LÄS MER
2. Some New Methods in Sialic Acid Chemistry
Sammanfattning : Gangliosides (G) are sialic acid-containing cell surface glycosphingolipids capable of forming lactones, i.e. inner esters. Some gangliosides are tumor-associated antigens, and they may serve as immunogens in their lactone form, where the latter is comparatively more abundant on the surface of malignant cells. LÄS MER
3. Sialic acid-dependent binding specificities of Helicobacter pylori and influenza virus. Importance of different parts of the binding sequences
Sammanfattning : Many viruses and bacteria adhere to host cell glycoconjugates in a specific manner, utilizing selected carbohydrate sequences. The aim of this work was to investigate at a molecular level the interactions of two important human pathogens, influenza virus and Helicobacter pylori, with sialylated carbohydrate structures. LÄS MER
4. Glycan-based interactions of Streptococcus pneumoniae and the host
Sammanfattning : Streptococcus pneumoniae is commonly found as an asymptomatic colonizer of the nasopharynx of children, but it can also translocate to normally sterile body sites and cause severe diseases, like pneumonia, septicemia or meningitis. Pneumococci spread via aerosols. LÄS MER
5. Structural studies on lipopolysaccharides from haemophilus species
Sammanfattning : Background: Carbohydrates are indispensable mediators for a variety of cellular interactions. In biological systems carbohydrates are usually linked to a carrier as e.g. proteins or lipids. LÄS MER
