Sökning: "Nerve fibers"

Visar resultat 1 - 5 av 109 avhandlingar innehållade orden Nerve fibers.

  1. 1. Morphometry of the Optic Nerve Head as a Diagnostic Tool for Glaucoma

    Författare :Camilla Sandberg Melin; Per Söderberg; Boel Bengtsson; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; optic nerve head; ONH; nerve fibers; glaucoma; optical coherence tomography; OCT; Pigment epithelium central limit-inner limit of the retina minimal distance; PIMD; PIMD-2π; Segmental PIMD-2π; confocal scanning laser tomography; HRT; NRA; variation; variability; variance; loss rate; follow-up.;

    Sammanfattning : Glaucoma is a chronic optic nerve head (ONH) disease. Gradual retinal ganglion cell and nerve fiber loss lead to morphological ONH change and visual field defects. Initial loss is often focal. Rate of progression and life expectancy guide treatment. LÄS MER

  3. 2. Vascular Endothelial Growth Factor (VEGF) and Peripheral Nerve Regeneration

    Författare :Mariann Sondell; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Schwann cell; SCG; rat; peripheral nerve regeneration; neuropilin-1; nerve repair; mouse; growth factor; flk-1; axonal outgrowth; DRG; VEGF; Animal physiology; Djurfysiologi;

    Sammanfattning : This thesis concerns vascular endothelial growth factor (VEGF) and its possible role as a neurotrophic factor. I have investigated the effect of VEGF on neurons in culture but also in vivo, following a crush lesion of the sciatic nerve, and following nerve repair. LÄS MER

  4. 3. 3D modelling of epidermal nerve fiber patterns

    Författare :Konstantinos Konstantinou; Chalmers University of Technology; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; diabetic neuropathy; Anisotropy; point processes.; epidermal nerve fibers;

    Sammanfattning : Neuropathical disorders, such as diabetic neuropathy, damage the nerve structure in the epidermis. This thesis presents statistical analyses and models for the epidermal nerve fibers (ENFs). The main objective is to improve our understanding regarding the three dimensional ENF structure and for this purpose, stochastic models are constructed. LÄS MER

  5. 4. Peripheral polyneuropathy in type 2 diabetes mellitus and impaired glucose tolerance. Correlations between morphology, neurophysiology, and clinical findings

    Författare :Soley Thrainsdottir; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nerve conduction studies; skin biopsy; intraepidermal nerve fibers; Diabetic neuropathy; sural nerve pathology; body mass index; quantitative sensory testing; vibrotactile sense;

    Sammanfattning : Diabetic peripheral polyneuropathy (PN) is a common and serious complication of diabetes. The prevalence of PN is rising with the global burden of type 2 diabetes. The causal mechanisms of PN are not fully understood, but both vascular and metabolic factors play a role. LÄS MER

  7. 5. Spatial analysis and modeling of nerve fiber patterns

    Författare :Claes Andersson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; Bayesian field theory; Diabetic neuropathies; Multilevel models Statistics ; Institutionen för matematiska vetenskaper. Tillämpad matematik och statistik.; CTH; hierarchical models; Bayesian estimation; epidermal nerve fibers; cluster processes; spatial point processes; diabetic neuropathy;

    Sammanfattning : Diabetic neuropathy is a condition associated with diabetes affecting the epidermal nerve fibers (ENFs). This thesis presents analysis methods and models for ENF data, with two main puroposes: to find early signs of diabetic neuropathy and to characterize how this condition changes the nerve fiber structure. LÄS MER