Sökning: "Neoadjuvant chemotherapy"

Visar resultat 1 - 5 av 44 avhandlingar innehållade orden Neoadjuvant chemotherapy.

  1. 1. Neoadjuvant chemotherapy in muscle-invasive urinary bladder cancer : studies on treatment response, tumor draining lymph nodes and blood transfusion

    Författare :Robert Rosenblatt; Amir Sherif; Ola Winqvist; Per Marits; Ralph Peeker; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bladder cancer; neoadjuvant chemotherapy; tumor downstaging; sentinel nodes; blood transfusion; Urology; kirurgi; särskilt urologi; Medicine; medicin;

    Sammanfattning : Muscle-invasive urinary bladder cancer is a deadly disease. Mortality rates remained unchanged for decades despite radical surgery.After several randomized trials, we today know that cisplatin based chemotherapy given prior to cystectomy, improves survival for every tenth patient. LÄS MER

  3. 2. Clinical and Experimental Studies in Peritoneal Metastases from Gastric Cancer

    Författare :Bo Hultman; Haile Mahteme; Bruno Walther; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastric cancer; peritoneal metastases; peritoneal carcinomatosis; epidemiology; prognostic factor; survival; neoadjuvant chemotherapy; cytoreductive surgery; HIPEC; health economy; costs; systemic chemotherapy; cultured tumor cells; fluorometric analysis; cancer drug tests; chemo-sensitivity; anti tumor drugs.; Surgery; Kirurgi;

    Sammanfattning : Gastric cancer (GC) is one of leading causes of death in the world, and peritoneal metastases (PM) are a major site of recurrence. PM from GC implies a poor prognosis, with median overall survival (mOS) approximately 3 months and no survival at five years. LÄS MER

  4. 3. Clinical aspects of cystectomy and urinary diversion

    Författare :Tomas Jerlström; Ove Andrén; Pernilla Sundqvist; Katja Fall; Jørgen Bjerggaard Jensen; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bladder cancer; urinary diversion; orthotopic neobladder substitution; postoperative complications; neoadjuvant chemotherapy; induction chemotherapy;

    Sammanfattning : The aim of this thesis was to explore different aspects of treatment of advanced urinary bladder cancer with radical cystectomy, pelvic lymph node dissection, and urinary diversion. Surgery that carry a high risk of complications as well as mortality. LÄS MER

  5. 4. Resection of colorectal liver metastases - Impact of preoperative chemotherapy

    Författare :Sam Eriksson; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal liver metastases; Preoperative chemotherapy; Liver resection; Hepatic microcirculation; Sarcopenia;

    Sammanfattning : Background Colorectal cancer is a leading cause of cancer related death worldwide. 20-30 % of patients will develop colorectal liver metastases (CRLMs). Surgical resection is the mainstay of treatment for CRLMs, and is often combined with perioperative chemotherapy, which can prolong progression-free survival after resection. LÄS MER

  7. 5. Experimental Diagnostics and Therapeutics of Invasive Urinary Bladder Cancer

    Författare :Amir Sherif; Per-Uno Malmström; Magnus Thörn; Lars Holmberg; Sten Nilsson; Michael J Droller; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Bladder cancer; Cystectomy; Neoadjuvant chemotherapy; Kirurgi; Lymph node excision; Radionuclide imaging; Gene expression; Surgery; Kirurgi; kirurgi; särskilt urologi; Urology;

    Sammanfattning : The two purposes of this thesis were to evaluate new diagnostic techniques of lymphnode staging in invasive bladder cancer and to evaluate the results of neoadjuvant chemotherapy in invasive bladder cancer.Sentinel node detection was performed in 13 patients in preparation for radical cystectomy. LÄS MER