Sökning: "Nelly Fransén"

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  1. 1. Studies on a Novel Powder Formulation for Nasal Drug Delivery

    Författare :Nelly Fransén; Erik Björk; Katarina Edsman; Lars Hovgaard; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nasal drug delivery; nasal powder spray; interactive mixture; mucoadhesion; sodium starch glycolate; superdisintegrant; bioavailability; clinical trial; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : Nasal administration has potential for the treatment of indications requiring a fast onset of effect or for drugs with low oral bioavailability. Liquid nasal sprays are relatively common, but can be associated with suboptimal absorption from the nasal cavity; this thesis shows that nasal absorption can be significantly enhanced with a dry powder formulation. LÄS MER