Sökning: "Needles"

Visar resultat 16 - 20 av 62 avhandlingar innehållade ordet Needles.

1. 16. Ceramic Materials for Administration of Potent Drugs

   Författare :Bing Cai; Susanne Bredenberg; Håkan Engqvist; Wei Xia; Miguel Manzano García; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Tamper-resistance; Oral formulation; Transdermal formulation; Biomaterials; Microneedles;

   Sammanfattning : This thesis aimed to investigate and document the potential of applying ceramics in two specific drug delivery applications: tamper-resistant opioid formulations and transdermal enhancement protrusions.Geopolymers were developed into the matrix for a tamper-resistant formulation, aiming to protect drug substances from non-medical abuse. LÄS MER

3. 17. Polymorphism and Crystallization of p-Aminobenzoic Acid

   Författare :Sandra Gracin; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; controlled crystallization; polymorphism; p-aminobenzoic acid;

   Sammanfattning : Polymorphs are solid phases where the chemical composition isequal but the crystal structure differs. Many organic compoundsmay appear in more than one crystalline structure. LÄS MER

4. 18. Proteomics and metabolomics in biological and medical applications

   Författare :Liudmila Shiryaeva; Wolfgang P. Schröder; Pernilla Wikström; Peter Roepstroff; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 2D-DIGE; biomarkers; cold-acclimation; conifer; freezing tolerance; GC-MS; metabolomics; multiple hypothesis test; multivariate analysis; OPLS-DA; Picea obovata; plasma; prostate cancer; proteomics; ProteoMiner; Siberian spruce;

   Sammanfattning : Biological processes in living organisms consist of a vast number of different molecular networks and interactions, which are complex and often hidden from our understanding. This work is focused on recovery of such details for two quite distant examples: acclimation to extreme freezing tolerance in Siberian spruce (Picea obovata) and detection of proteins associated with prostate cancer. LÄS MER

5. 19. Acupuncture for labour pain

   Författare :Linda Vixner; Lena Mårtensson; Erica Schytt; Elisabet Stener-Victorin; Ulla Waldenström; Mats Hammar; Högskolan Dalarna; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acupuncture; labour pain; randomised controlled trial; Hälsa och välfärd; Health and Welfare;

   Sammanfattning : Background: Acupuncture involves puncturing the skin with thin sterile needles at defined acupuncture points. Previous studies are inconclusive regarding the effect of acupuncture on labour pain, but some studies have found a reduction in the use of pharmacological pain relief when acupuncture is administered. LÄS MER

7. 20. A Fully Integrated Microneedle-based Transdermal Drug Delivery System

   Författare :Niclas Roxhed; Göran Stemme; Mark G. Allen; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microneedle; Transdermal; Intradermal; Drug delivery; DRIE; MEMS; Microsystem; Medical technology; Medicinsk teknik;

   Sammanfattning : Patch-based transdermal drug delivery offers a convenient way to administer drugs without the drawbacks of standard hypodermic injections relating to issues such as patient acceptability and injection safety. However, conventional transdermal drug delivery is limited to therapeutics where the drug can diffuse across the skin barrier. LÄS MER