Sökning: "Necrotizing"

Visar resultat 1 - 5 av 29 avhandlingar innehållade ordet Necrotizing.

1. 1. Experimental and Clinical Necrotizing Enterocolitis

   Författare :Niclas Högberg; Heléne Engstrand Lilja; Agneta Nordenskjöld; Uppsala universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Necrotizing; Enterocolitis; Ischemia; Microdialysis; Intraluminal; I-FABP; Kirurgi; särskilt barnkirurgi; Pediatric Surgery;

   Sammanfattning : Necrotizing enterocolitis (NEC), a severe inflammatory disorder of the gastrointestinal tract with high morbidity and mortality, affects primarily preterm infants. The diagnosis represents a challenging task, and no biomarker has been found to aid early diagnosis with high accuracy. LÄS MER

3. 2. Necrotizing enterocolitis : imaging and risk assessment

   Författare :Elena Palleri; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

   Sammanfattning : Despite decades of research on necrotizing enterocolitis (NEC), no major finding has improved the mortality and morbidity of the disease or changed the clinical management. The exact pathogenesis remains unclear, but several factors such as immature intestinal immunity, impaired bowel microcirculation, enteral nutrition and abnormal microbiota may play important roles. LÄS MER

4. 3. On community acquired infections requiring intensive care

   Författare :Magnus Brink; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intensive care; infection; acute bacterial meningitis; beta-lactam antibiotics; cerebrospinal fluid; polymerase chain reaction; immunochromatographic test; influenza A H1N1; pandemic; non-invasive ventilation; necrotizing soft-tissue infection; inter-hospital transfer;

   Sammanfattning : Acute bacterial meningitis (ABM), influenza, and necrotizing soft-tissue infections (NSTIs) are diseases that in a short period of time can progress to become life threatening. Individuals with severe forms of these infections must be treated in an intensive care unit were monitoring and support of failing organs improve the chances of survival. LÄS MER

5. 4. Receptor Interactions Between Pathogenic Bacteria and Host Cells

   Författare :Lena Lövkvist; Ann-Beth Jonsson; Heiko Herwald; Uppsala universitet; []
   Nyckelord :Microbiology; Type IV pili; Lipooligosaccharide; ScpC protease; CD46; Mikrobiologi;

   Sammanfattning : This thesis focuses on host and pathogen specific interactions during invasive disease. We have investigated the role and impact of different virulence factors of Neisseria gonorrhoeae, N. meningitidis and Streptococcus pyogenes on host epithelial cells and in vivo. N. LÄS MER

7. 5. T lymphocytes in Wegener's granulomatosis

   Författare :Ricardo Antonio Giscombe Stephen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Wegener s granulomatosis; T lymphocytes; TCR; T cell expansions; HLA-DRB1*0401; CTLA-4; IL-10;

   Sammanfattning : Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis that affects small and medium size blood vessels. The respiratory tract and lungs are usually compromised with necrotizing granulomatous formations. The aetiology is unknown and untreated the prognosis of generalised WG is very poor. LÄS MER