Visar resultat 1 - 5 av 29 avhandlingar innehållade ordet Necrotizing.
Sammanfattning : Necrotizing enterocolitis (NEC), a severe inflammatory disorder of the gastrointestinal tract with high morbidity and mortality, affects primarily preterm infants. The diagnosis represents a challenging task, and no biomarker has been found to aid early diagnosis with high accuracy. LÄS MER
Sammanfattning : Despite decades of research on necrotizing enterocolitis (NEC), no major finding has improved the mortality and morbidity of the disease or changed the clinical management. The exact pathogenesis remains unclear, but several factors such as immature intestinal immunity, impaired bowel microcirculation, enteral nutrition and abnormal microbiota may play important roles. LÄS MER
Sammanfattning : Acute bacterial meningitis (ABM), influenza, and necrotizing soft-tissue infections (NSTIs) are diseases that in a short period of time can progress to become life threatening. Individuals with severe forms of these infections must be treated in an intensive care unit were monitoring and support of failing organs improve the chances of survival. LÄS MER
Sammanfattning : This thesis focuses on host and pathogen specific interactions during invasive disease. We have investigated the role and impact of different virulence factors of Neisseria gonorrhoeae, N. meningitidis and Streptococcus pyogenes on host epithelial cells and in vivo. N. LÄS MER
Sammanfattning : Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis that affects small and medium size blood vessels. The respiratory tract and lungs are usually compromised with necrotizing granulomatous formations. The aetiology is unknown and untreated the prognosis of generalised WG is very poor. LÄS MER