Sökning: "Natural killer cell"

Visar resultat 21 - 25 av 197 avhandlingar innehållade orden Natural killer cell.

  1. 21. Functional and molecular aspects of interferon action in human natural killer cells and other leucocytes

    Författare :Åke Gustafsson; Erik Lundgren; Umeå universitet; []
    Nyckelord :natural killer cell; large granular lymphocyte; interferon; interferon production; interferon-induced; protein synthesis; two-dimensional electrophoresis;

    Sammanfattning : Interferons comprise a class of structurally related proteins which exert several regulatory effects in responsive cells. These effects include the establishment of an antiviral state, the inhibition of cellular proliferation and the alteration of different immune reactions. LÄS MER

  3. 22. Mechanisms influencing natural killer cell recognition of tumour cells

    Författare :Monika Enqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Natural killer (NK) cells are part of our innate immune defence against virus-infected and transformed cells. Through a yet undefined mechanism, expression of inhibitory receptors for self-HLA class I molecules endow NK cells with increased functionality. The process leading to gain of function through inhibition is known as NK cell education. LÄS MER

  4. 23. Oxidant-induced cell death in lymphocytes: mechanisms of induction and resistance

    Författare :Fredrik Bergh Thorén; Göteborgs universitet; []
    Nyckelord :reactive oxygen species; cell death; apoptosis; poly ADP-ribose polymerase-1; apoptosis-inducing factor; natural killer cells; phagocytes; dendritic cells;

    Sammanfattning : Reactive oxygen species (oxidants, oxygen radicals) produced by the phagocytic NADPH oxidase have pivotal roles in immunity. Patients lacking a functional NADPH oxidase suffer from chronic granulomatous disease, which is characterized by recurring bacterial infections and thus manifesting the importance of reactive oxygen species in host defense against bacteria. LÄS MER

  5. 24. Microscopy-based single-cell in vitro assays for NK cell function in 2-D and 3-D

    Författare :Per Erik Olofsson; Björn Önfelt; Khakoo Salim; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biological Physics; Biologisk fysik;

    Sammanfattning : Natural killer (NK) cells are effector cells of the innate immune system that are responsible for mediating cellular cytotoxicity against virally infected or neoplastically transformed cells. NK cell subsets are defined by their expression of certain cell-surface markers, and are usually related to activation and developmental status. LÄS MER

  7. 25. Pathogenesis and Cell Biology of the Salmon Parasite Spironucleus salmonicida

    Författare :Ásgeir Ástvaldsson; Staffan Svärd; Jon Jerlström-Hultqvist; Scott Dawson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Diplomonads; Spironucleus; Giardia; genome; annexin; oxygen stress; APEX; pathology;

    Sammanfattning : Spironucleus species are classified as diplomonad organisms, diverse eukaryotic flagellates found in oxygen-deprived environments. Members of Spironucleus are parasitic and can infect a variety of hosts, such as mice and birds, while the majority are found to infect fish. LÄS MER