Sökning: "Natural killer NK cells"

Visar resultat 11 - 15 av 156 avhandlingar innehållade orden Natural killer NK cells.

  1. 11. Therapeutic potential of natural killer cells in multiple myeloma

    Författare :Evren Alici; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Natural Killer cells; immunotherapy; multiple myeloma; gene therapy;

    Sammanfattning : Multiple Myeloma (MM) is an incurable plasma cell neoplasm with a median length of survival after diagnosis of approximately three years; therefore new treatment modalities to eradicate the disease are needed. Although the disease remains incurable, current main alternatives are drug treatment modalities and autologous stem cell transplantation (ASCT). LÄS MER

  3. 12. Immuno-modulatory functions of CD1d-restricted natural killer T cells

    Författare :Emma Berntman; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serologi; serology; Immunology; Medicin människa och djur ; Medicine human and vertebrates ; microarray; gene expression signature; infection; Salmonella; CD1d; NKT cells;

    Sammanfattning : This thesis focuses on a small population of non-conventional T lymphocytes, called natural killer T (NKT) cells. NKT cells have many unique features; such as recognition of glycolipids presented by CD1d, expression of NK receptors and rapid production of large amounts of cytokines, such as IL-4 and IFN-gamma,?upon activation. LÄS MER

  4. 13. Diversity of CD1d-restricted natural killer T cells

    Författare :Markus Sköld; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; autoreactive; Ly49 receptor; CD1d; NKT cell; transplantation; Immunologi; serologi;

    Sammanfattning : The present study deals with natural killer (NK) T cells restricted to the antigen presenting molecule CD1d. NKT cells have been suggested to play a role in many diverse immunological situations such as clearance of different pathogens, protection against certain tumors, regulation of autoimmune reactions and as a link between innate and adaptive immune responses. LÄS MER

  5. 14. Phenotypic and functional studies of NK cells in neonates and during early childhood

    Författare :Yvonne Sundström; Marita Troye-Blomberg; Louise Berg; Eleanor Riley; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : During infancy, before adaptive immunity has matured, innate immunity is thought to be relatively more important. Human natural killer (NK) cells are innate immune cells involved in the control of virus-infected cells and can influence adaptive immunity mainly through cytokine production. LÄS MER

  7. 15. Regulation of Type I Interferon Production in Plasmacytoid Dendritic Cells : Effect of Genetic Factors and Interactions with NK Cells and B Cells

    Författare :Olof Berggren; Maija-Leena Eloranta; Niels Heegaard; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic lupus erythemtosus; IFN-alpha; autoimmunity; immune complex; single nuclear polymorphisms; Medicinsk vetenskap; Medical Science;

    Sammanfattning : The type I interferon (IFN) system plays a central role in the etiopathogenesis of many autoimmune diseases, e.g. systemic lupus erythematosus (SLE). Activation of the type I IFN system in SLE is promoted by endogenous nucleic acid-containing immune complexes (ICs) which stimulate plasmacytoid dendritic cells (pDCs). LÄS MER