Sökning: "Natriuretic peptide"
Visar resultat 11 - 15 av 90 avhandlingar innehållade orden Natriuretic peptide.
11. Heart failure : biomarker effect and influence on quality of life
Sammanfattning : Background and aims: Heart failure (HF) is a life threatening condition and optimal handling is necessary to reduce risk of therapy failure. The aims of this thesis were: (Paper I) to examine whether BNP (B-type natriuretic peptide)-guided HF treatment improves morbidity and mortality when compared with HF therapy implemented by a treating physician at sites experienced in managing patients with HF according to guidelines; (Paper II) to investigate how to define a responder regarding optimal cut-off level of BNP to predict death, need for hospitalisation, and worsening HF and to determine the optimal time to apply the chosen cut-off value; (Paper III) to evaluate how Health-Related Quality of Life (HR-QoL) is influenced by natriuretic peptide guiding and to study how HR-QoL is affected in responders compared to non-responders; (Paper IV) to evaluate the impact of patient age on clinical outcomes, and to evaluate the impact of duration of the HF disease on outcomes and the impact of age and HF duration on BNP concentration. LÄS MER
12. Peptide and non-peptide biomarkers of mortality in patients with advanced chronic kidney disease
Sammanfattning : Over the last decade, multiple studies have attempted to identify better risk prediction tools specific to the chronic kidney disease (CKD) population. In many cases, these studies have evaluated the use of various peptide biomarkers as prediction tools. LÄS MER
13. Echocardiographic assessment and B-type natriuretic peptide for risk evaluation in acute coronary syndromes
Sammanfattning : Acute coronary syndromes (ACS) is one of the most common causes of emergency medical care and the single most common cause of death in Sweden in both men and women. Despite a significant improvement in survival in the acute phase, the frequency of rehospitalization and death in subsequent years is unacceptably high. LÄS MER
14. Natriuretic Peptides and the Microcirkulation in Heart Failure Patients
Sammanfattning : The increased prevalence of chronic congestive heart failure (HF) is a tremendous challenge for society. In spite of effective medical treatment for acute HF, better pharmacological treatment for specific neurohormonal intervention and better diagnostic tools, e.g. LÄS MER
15. Blood pressure-dependent changes in plasma volume, glycocalyx and platelet function during anaesthesia -Clinical and experimental studies
Sammanfattning : Background: Worldwide, more than 300 million surgeries are performed each year. General anaesthesia provides the surgical patient with a state of controlled loss of sensation and awareness. It is common that general anaesthesia causes hypotension. Anaesthesia-induced hypotension is associated with haemodilution and increased plasma volume (PV). LÄS MER