Sökning: "Naphthoxylosides"
Hittade 4 avhandlingar innehållade ordet Naphthoxylosides.
1. Naphthoxylosides Investigations into glycosaminoglycan biosynthesis
Sammanfattning : Glycosaminoglycans (GAGs) are members of a family of polysaccharide structures consisting mostly of repeating disaccharide units. Most GAGs are attached to specific serine residues in proteins to form proteoglycans (PGs). LÄS MER
2. Synthetic studies on naphthoxylosides - labeled compounds and mechanistic studies on acetals
Sammanfattning : Labeled analogs to an antiproliferative naphthoxyloside have been synthesized and evaluated. Our investigations have shown that the fluorescently labeled analogs are poor structural analogs, and the physical and biological properties are altered to a large extent. LÄS MER
3. Tumor Selective Antiproliferative Naphthoxylosides
Sammanfattning : Proteoglycans (PG) are highly anionic macromolecules consisting of a core protein covalently substituted with long unbranched polysaccharide chains called glycosaminoglycans (GAGs). PGs are central components in multicellular organisms, and they may occur in the extracellular matrix (ECM), at the cell surface, or in the secretory pathway. LÄS MER
4. Naphthoxylosides – Probing the β4GalT7 active site
Sammanfattning : Proteoglycans (PGs) is a class of highly anionic macromolecules that consist of one or more linear polysaccharide chains (glycosaminoglycans, GAGs) covalently attached to a core protein. The biological functions of PGs are mainly due to the interactions of GAG chains with various protein ligands and regulatory factors, such as cytokines and growth factors. LÄS MER