Sökning: "Naida Suleymanova"

Hittade 1 avhandling innehållade orden Naida Suleymanova.

  1. 1. Beta-arrestins in cancer : linking pro-tumorigenic extracellular activated signaling with the tumor suppressor p53 pathway

    Författare :Naida Suleymanova; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The IGF-1R is an important player in cancer development that maintains the malignant phenotype by inducing cell proliferation, survival, transformation, motility and invasiveness. Activation of IGF-R results in its Mdm2-dependent ubiquitination and degradation followed by MAPK signaling. LÄS MER