Sökning: "NTP"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet NTP.

  1. 1. Targeting the nucleotide metabolism of the mammalian pathogen Trypanosoma brucei

    Författare :Munender Vodnala; Anders Hofer; Arne Holmgren; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Trypanosoma brucei; adenosine kinase; thymidine kinase; methylthioadenosine phosphorylase; mouser ribonucleotide reductase; E. coli ribonucleotide reductase; RNR; Ara-A; F-Ara-A; dNTP; NTP; doexynucleotide metabolism; nucleosides; nucleoside kinases; allosteric regulation; biologisk kemi; biological chemistry;

    Sammanfattning : Trypanosoma brucei causes African sleeping sickness in humans and Nagana in cattle. There are no vaccines available against the disease and the current treatment is also not satisfactory because of inefficacy and numerous side effects of the used drugs.T. LÄS MER

  3. 2. Access to tuberculosis care in rural China : comparing the impact of alternative control projects

    Författare :Biao Xu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Tuberculosis; DOTS; socioeconomic status; diagnostic delay; expenditure; health care seeking; rural; China;

    Sammanfattning : Background: China has the second highest burden of tuberculosis (TB) worldwide. The modern TB control strategies Directly Observed Treatment, Short Course (DOTS) has, since 1992, been adopted by the National TB Control Programme (NTP) with subsidized or free TB care to smear-positive TB patients. LÄS MER

  4. 3. Global policy to local implementation : experiences from active tuberculosis case-finding in high-burden countries

    Författare :Olivia Biermann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Tuberculosis (TB) is one of the world’s leading infectious killers. Every year, an estimated 10 million people fall ill with the disease, of whom 2.9 million people are never diagnosed and treated. Thirty low- and middle-income countries account for almost 90% of the global TB burden. LÄS MER

  5. 4. Tuberculosis control in Vietnam : directly observed treatment, short-course (DOTS) : the role of information and education

    Författare :Nguyen Phuong Hoa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Tuberculosis; DOTS; knowledge; practice; health seeking behaviour; case detection; Vietnam.;

    Sammanfattning : Background: In 1993, the WHO declared tuberculosis (TB) a global emergency. At the same time, the DOTS strategy was recommended for controlling TB. DOTS focuses on sputum smear positive pulmonary TB patients who present themselves to a health facility for diagnosis. LÄS MER

  7. 5. Gender differences in chemical carcinogenesis

    Författare :Sandeep Kadekar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Gender differences in cancer incidence and mortality is a regular finding in epidemiological studies. In addition to reproductive organs this pattern is also seen in non-reproductive organs, with men being the most affected gender for the majority of cancer-sites. LÄS MER