Sökning: "NSPHS"

Hittade 2 avhandlingar innehållade ordet NSPHS.

  1. 1. The effect of common and rare variants on inflammatory traits and diseases

    Författare :Julia Höglund; Åsa Johansson; Matthew Robinson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GWAS; inflammation; biomarkers; WES; WGS; NSPHS; UK Biobank; association study;

    Sammanfattning : Genome wide association studies (GWAS) have identified thousands of loci associated to an immense number of traits and diseases. Most associations have been to common variants, but rare variant associations are progressively being reported. LÄS MER

  3. 2. Evolution of Membrane Bound Proteins and their Ligands : The Melanocortin (MC) Receptor Inverse Agonists AgRP2, ASIP2, Drug/Metabolite Transporters, and SPNS1

    Författare :Åke Västermark; Helgi Schiöth; Arne Elofsson; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : Integral membrane proteins play a key role hormonal and neuronal signaling. Transmembrane helix (TM) proteins form about 27% of the human proteome. Furthermore, 44% of the human drug targets are receptors, and 19% of these are seven-transmembrane domain receptors (GPCRs), which constitute 4% of the entire protein-coding genome. LÄS MER