Sökning: "NSAID"

Visar resultat 11 - 15 av 47 avhandlingar innehållade ordet NSAID.

1. 11. Improving medical abortion : using mifepristone in combination with a prostaglandin analogue

   Författare :Christian Fiala; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Medical abortion; mifepristone; misoprostol; slow release; home use; hCG; ultrasound; verification of expulsion; non-steroidal anti-inflammatory drug; pain relief; second trimester; uterine contractility; acceptability;

   Sammanfattning : Background: Induced abortion is still a major health problem in the world and the most frequently performed intervention in Obstetrics and Gynaecology with an estimated total of 46 millions worldwide each year. Medical abortion with mifepristone and prostaglandin was first introduced in 1988, and is now approved in 29 countries. LÄS MER

3. 12. Gastric acid secretion and gut peptides : mechanisms involved in inflammatory response

   Författare :Tobias Rudholm Feldreich; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The regulation of gastric acid secretion is complex and involves endocrine, paracrine, and neurocrine mechanisms. Among these, the interconnecting cross-talk between different gut peptides is an important part in the control of acid secretion. LÄS MER

4. 13. Acute postoperative and cancer-related pain management, Patients´ experiences and perceptions in relation to health-related quality of life and the multidimensionality of pain

   Författare :Barbro Boström; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anestesiologi; intensivvård; intensive care; Anaesthesiology; SF-36.; postoperative pain; Pain-o-Meter; perceptions; pain management; nursing care; Health-Related Quality of Life; American Pain Society; cancer-related pain; American Pain Society; MEDICINE;

   Sammanfattning : This thesis describes patients in acute postoperative pain as well as patients with acute cancer-related pain in palliative care, and their experiences and perceptions of pain management in relation to HRQOL and the multidimensionality of pain. A combination of qualitative and quantitative methods was chosen. LÄS MER

5. 14. Angiotensin converting enzyme inhibition and aspirin in congestive heart failure

   Författare :Tord Juhlin; Kardiologiska klinikens forskargrupp; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clinical trial; ARBs; renal function; congestive heart failure; ischaemic heart disease; NSAIDs; ACE-inhibitors; aspirin; dose dependency; Cardiovascular system; Kardiovaskulära systemet;

   Sammanfattning : Angiotensin-converting enzyme (ACE) inhibitors act by decreasing production of angiotensin II and by potentiating the effects of bradykinin by inhibition of its breakdown. Bradykinin exerts part of its effects via vasodilating prostaglandins. Since the cyclooxygenase (COX)-inhibitors, e.g. LÄS MER

7. 15. Studies on intrinsic and extrinsic sources of variability in pharmacokinetics and pharmacodynamics

   Författare :Johanna Mercke Odeberg; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxikologi; pharmacy; pharmacognosy; Pharmacological sciences; Medicin människa och djur ; Medicine human and vertebrates ; genetic polymorphisms UGT1A-and MDR1 gene ; indirect response model; desmopressin; oral lipid based formulations; farmaci; Farmakologi; toxicology; farmakognosi;

   Sammanfattning : Variability in pharmacokinetic and pharmacodynamic parameters between individuals can be due to intrinsic and extrinsic factors. In this thesis three different areas regarding sources of variability have been investigated. 1. Formulation properties as an extrinsic source of variability. LÄS MER