Sökning: "NS3 protease inhibitors"
Visar resultat 26 - 27 av 27 avhandlingar innehållade orden NS3 protease inhibitors.
26. Discovery and evaluation of direct acting antivirals against hepatitis C virus
Sammanfattning : Until recently, the standard therapy for hepatitis C treatment has been interferon and ribavirin. Such treatment has only 50% efficacy and is not well tolerated. The emergence of new drugs has increased the treatment efficacy to 90%. LÄS MER
27. Generation of polyfunctional T cells against HCV by T cell redirection and vaccination
Sammanfattning : The hepatitis C virus (HCV) is the major cause of liver disease and it is estimated that around 170 millions of people are infected worldwide. The available therapy is a combination of pegylated-interferon-alpha, ribavirin and since 2011, also NS3/4A protease inhibitors boceprevir and telaprevir. LÄS MER