Sökning: "NPY Y1 receptor"

Visar resultat 1 - 5 av 26 avhandlingar innehållade orden NPY Y1 receptor.

  1. 1. Neuropeptide Y - aspects of vasomotorresponses and receptor characterization

    Författare :Torun Nilsson-Bergdahl; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vasoconstriction; RT-PCR; receptor characterization; potentiation; NPY Y1 receptor; NPY; mitogenesis; hypertension; human arteries; forearm blood flow; cell culture; antisense oligodeoxynucleotides; BIBP3226; vasodilatation.; Physiology; Fysiologi; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Abstract The aims of the present thesis were to examine neuropeptide Y (NPY) responses in different human and guinea pig vascular beds and in cultured human vascular smooth muscle cells (VSMC) and to characterize, with different NPY agonists and the specific NPY Y1 receptor antagonist (BIBP3226), the NPY receptors involved. NPY-induced strong and potent contractions in human cerebral and subcutaneous arteries and in guinea pig basilar arteries. LÄS MER

  2. 2. Studies of the Neuropeptide Y Receptor Y2 in Human and Zebrafish

    Författare :Helena Fällmar; Dan Larhammar; Ingrid Lundell; Nina Mohell; Raquel E. Rodríguez Rodríguez; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Y2-receptor; NPY; PYY; G-protein-coupled receptor; mutagenesis; receptor binding; zebrafish; evolution; Pharmacology; Farmakologi; Farmakologi; Pharmacology;

    Sammanfattning : The G-protein coupled receptors (GPCRs) comprise the largest family of receptors in humans and other vertebrates. They are embedded in the cell membrane and are activated by many different signaling molecules. Activation modulates cellular signal transduction pathways and influences many physiological processes. LÄS MER

  3. 3. Neuropeptide Y Y1 receptor mechanisms in sympathetic vascular control

    Författare :Rickard E. Malmström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Sympathetic vasoconstriction; neuropeptide Y1 Y; receptor antagonists; BIBP 3226; SR 120107A; ischaemia; pig.;

    Sammanfattning : Neuropeptide Y Yl receptor mechanisms in sympathetic vascular control. By Rickard E. Malmström, 1997. Department of Physiology and Pharmacology, Karolinska Institute, S- 17177 Stockholm, Sweden. LÄS MER

  4. 4. Molecular characterization of the neuropeptide Y family and the NPY receptor Y1

    Författare :Anders G. Blomqvist; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  5. 5. Molecular Evolution of Neuropeptide Y Receptors in Vertebrates

    Författare :Erik Salaneck; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Neuropeptide Y; Receptor; Evolution; Neurovetenskap; Neurology; Neurologi; Neurology; neurologi;

    Sammanfattning : The three evolutionarily related peptides neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP) are ligands to at least five G-protein coupled receptors in mammals, which are denoted by numbers. NPY has many physiological effects including stimulation of appetite and regulation of circadian rhythm and blood pressure. LÄS MER