Sökning: "NOD mice"

Visar resultat 11 - 15 av 59 avhandlingar innehållade orden NOD mice.

  1. 11. Expreession of Somatostatin Receptor Subtypes in Pancreatic Islets of Normal Mice, Rats and Diabetic NOD Mice

    Författare :Eva Ludvigsen; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  3. 12. Functional studies of candidate genes contributing to type 1 diabetes in the NOD mouse

    Författare :Marie Lundholm; Dan Holmberg; Vivianne Malmström; Umeå universitet; []
    Nyckelord :Type 1 Diabetes; NOD mouse; CTLA-4; Ctex; CD3ζ; apoptosis; Idd6; Lrmp; medicinsk genetik; Medical Genetics;

    Sammanfattning : Type 1 Diabetes (T1D) is an autoimmune disorder caused by both genetic and environmental factors. The non-obese diabetic (NOD) mouse is one of the best and most commonly studied animal models for T1D. This mouse strain spontaneously develops diabetes through a process that closely resembles the human pathogenesis. LÄS MER

  4. 13. Cellular and genetic components in the development of IDDM in NOD mice

    Författare :Kristina Lejon; Dan Holmberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; non-obese diabetic; IgVh gene utilisation; immunoregulation; programmed cell death; genetic linkage analysis; immunologi; Immunology;

    Sammanfattning : .... LÄS MER

  5. 14. Humanized mice as a model to study human immunity

    Författare :Frank Heuts; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mice with human immune systems have evolved over the last three decades. Over the years, these humanized mouse models have provided us with valuable information on human immunity. Recent developments in recipient mouse strains and engraftment protocols have resulted in models with high level of de novo formation of human immune cells. LÄS MER

  7. 15. Metab-Immune analysis of the non-obese diabetic mouse

    Författare :Viqar Banday; Kristina Lejon; Åsa Andersson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NOD mouse; Type 1 diabetes; B cells; glutamic acid; metabolomics; immunologi; Immunology;

    Sammanfattning : Type 1A diabetes mellitus or T1D is a chronic disease characterized by T cell mediated destruction of the insulin producing β cells in the islets of Langerhans. The classical symptoms include high glucose levels in urine and blood, polyuria, and polydipsia. LÄS MER