Sökning: "NMR nuclear magnetic resonance"

Visar resultat 1 - 5 av 214 avhandlingar innehållade orden NMR nuclear magnetic resonance.

1. 1. Nuclear Magnetic Relaxation in Micellar Solution and Lyotropic Liquid Crystals. Tools and Applications

   Författare :Ruslan Sitnikov; KTH; []
   Nyckelord :NMR; NMR relaxation dispersion; NMR spectrometer; low NMR frequencies; NMR duplexer; NMR preamplifier; NMR lock; surfactant systems; micellar solutions; lyotropic liquid crystals; cubic mesophase;

   Sammanfattning : Structurally, this Thesis is divided into two parts thatdescribe (i) the hardware development for NMR relaxationstudies and (ii) its applications for studies of the surfactantsystems.The developed hardware solutions allow to expand thefrequency range covered by conventional NMR spectrometers tomake NMR experiments feasible at resonance frequencies down to100 kHz. LÄS MER

3. 2. Characterizing Chromatography Media : NMR-based Approaches

   Författare :Fredrik Elwinger; István Furó; Stéphane Viel; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chromatography; nuclear magnetic resonance; NMR; self-diffusion; magic-angle spinning; quantitative; distribution coefficient; pore size; Kemi; Chemistry;

   Sammanfattning : Liquid chromatography is an essential technique in manufacturing biopharmaceuticals where it is used on all scales from analytical applications in R&D to full-scale production. In chromatography the target molecule, typically a protein, is separated and purified from other components and contaminants. LÄS MER

4. 3. Development and applications of NMR relaxation methods to study protein and ligand dynamics

   Författare :Sven Wernersson; Biofysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nuclear magnetic resonance; NMR; NMR relaxation; Method development; Protein dynamics; BRD4; Galectin 3; Kärnmagnetisk resonansspektroskopi; proteindynamik; Metodutveckling; NMR; BRD4; Galektin 3;

   Sammanfattning : This thesis involves the study of proteins. These molecules exist in many variants, and perform most of our bodily functions. This includes signaling (for example the presence of capsaicin, which makes food spicy), molecular transport (including oxygen), catalysis (including food digestion) and part of our body structure (such as muscles). LÄS MER

5. 4. Molecular recognition and dynamics in proteins studied by NMR

   Författare :Johan Wallerstein; Biofysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Chemical exchange; Conformational entropy; Entropy; Galectin-3; Isothermal Titration Calorimetry; ITC; Model-free formalism; Molecular recognition; Nuclear Magnetic Resonance; NMR; PGB1; Protein dynamics; Protein–ligand interactions; Proton-transfer reactions; Spin relaxation; Viscosity; Chemical exchange; Conformational entropy; Entropy; Galectin-3; Isothermal Titration Calorimetry; ITC; Model-free formalism; Molecular recognition; Nuclear Magnetic Resonance; NMR; PGB1; Protein dynamics; Protein–ligand interactions; Proton-transfer reactions; Spin relaxation; Viscosity;

   Sammanfattning : Knowledge of dynamics in protein is very important in the description of protein function and molecular recognition. The thesis investigates protein dynamics on time-scales from milli- to sub-nanosecond, with focus on the latter, using NMR spin relaxation experiments on two proteins, the 138-residue carbohydrate recognition domain of galectin-3 (Gal3C) and the 56-residue B1 domain of bacterial protein G (PGB1). LÄS MER

7. 5. NMR Imaging of Flow and Perfusion using Hyperpolarized Nuclei: Theoretical Considerations and Application to Experimental Models

   Författare :Edvin Johansson; Lund Medicinsk strålningsfysik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nukleärmedicin; radiobiologi; radiobiology; Nuclear medicine; Perfusion; Macroscopic flow; Hyperpolarized tracers; Nuclear magnetic resonance NMR ; Magnetic resonance imaging MRI ;

   Sammanfattning : In the studies presented in this thesis, hyperpolarized tracers have been used for the study of macroscopic flow and capillary perfusion with magnetic resonance imaging. The feasibility of performing vascular studies using echo-planar imaging (EPI) and hyperpolarized 129Xe was investigated using xenon dissolved in ethanol prior to injection into a flow phantom. LÄS MER