Sökning: "NMR and electrospray ionization mass spectrometry ESI-MS"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden NMR and electrospray ionization mass spectrometry ESI-MS.

1. 1. Electrospray Ionization Mass Spectrometry for Determination of Noncovalent Interactions in Drug Discovery

   Författare :Kurt Benkestock; Johan Roeraade; Renato Zenobi; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; electrospray ionization; drug discovery; noncovalent interaction; complexes; human serum albumin HSA ; fatty acid binding protein FABP ; ribonuclease; ligand screening; Analytical chemistry; Analytisk kemi;

   Sammanfattning : Noncovalent interactions are involved in many biological processes in which biomolecules bind specifically and reversibly to a partner. Often, proteins do not have a biological activity without the presence of a partner, a ligand. LÄS MER

3. 2. Catalytic and Electrocatalytic Transformations with Palladium and Nickel : Scope and mechanistic investigations

   Författare :Alejandro Valiente Sánchez; Belén Martín-Matute; King Kuok (Mimi) Hii; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; Heterogeneous Catalysis; Metal-organic frameworks; Nickel; Palladium; Electrocatalysis; Cross-coupling; Hydrogenation; organisk kemi; Organic Chemistry;

   Sammanfattning : The work presented in this thesis is based on methodology development and mechanistic investigations using heterogeneous palladium and nickel catalysts. Following the introduction (Chapter 1), Chapter 2 presents a summary of the synthesis and characterization of the MOF-supported Pd catalysts (Pd @ MOF) that are used in this thesis. LÄS MER

4. 3. Structural diversity of the lipid A and core oligosaccharide moieties of the lipopolysaccharides from nontypeable and serotype f Haemophilus influenzae

   Författare :Håkan H. Yildirim; Elke Schweda; Andrzej Gamian; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Haemophilus influenzae; LPS; biosynthesis; NMR; ESI-MS;

   Sammanfattning : This thesis describes structural studies of the oligosaccharide and lipid A moieties of lipopolysaccharides (LPSs) isolated from disease-causing Haemophilus influenzae strains. The nontypeable strains were clinical isolates from the middle ear of children suffering from otitis media and the serotype f strains had been collected from three adults with respiratory tract infections. LÄS MER

5. 4. Fundamental Characterization and Technical Aspects of a Chelating Surfactant

   Författare :Ida Svanedal; Håkan Edlund; Magnus Norgren; Krister Holmberg; Mittuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chelating surfactant; DTPA based surfactant; pH-responsive; characterization; surface tension; NMR diffusometry; conditional stability constants; interaction parameter; ion flotation;

   Sammanfattning : The purpose of this study was to investigate the fundamental characteristics of a chelating surfactant in terms of solution behaviour, chelation of divalent metal ions, and interaction in mixtures with different foaming agents and divalent metal ion, as well as examining its prospects in some practical applications. Chelating surfactants are functional molecules, with both surface active and chelating properties, which are water soluble and therefore suitable for chelation in many aqueous environments. LÄS MER

7. 5. Analytical approaches to the study of mucin glycosylation

   Författare :Kristina A Thomsson; Göteborgs universitet; []
   Nyckelord :mucins; O-linked glycosylation; mass spectrometry; cystic fibrosis; salivary mucins; sulfated oligosaccharides.;

   Sammanfattning : Mucins constitute the major protein component of the mucus layer, which covers the epithelial surfaces of the respiratory, the gastrointestinal and the genitourinary tracts. Mucins carry O-linked oligosaccharides which contribute to the molecule by 50-80 weight percent, and these can be highly diverse, with 50-150 different oligosaccharides found on a purified mucin population. LÄS MER