Sökning: "NMDA"

Visar resultat 6 - 10 av 155 avhandlingar innehållade ordet NMDA.

  1. 6. Role of environmental toxins in chronic experimental arthrithis - in search for anti-inflammatory pathways of ethanol and nicotine

    Författare :Sofia Silfverswärd Lindblad; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; collagen-induced arthritis; ethanol; testosterone; nuclear factor kappa B; smoking; nicotine; NMDA; regulatory T cells;

    Sammanfattning : Rheumatoid arthritis (RA) is a common systemic autoimmune disorder and a debilitating disease affecting 1% of the world population. The etiology of RA is an unresolved issue. Environmental factors such as alcohol intake and cigarette smoke have been described as contributing to the pathogenesis of RA. LÄS MER

  2. 7. Differences in glutamatergic transmission onto interneurons and pyramidal cells in the rat hippocampus

    Författare :Ilse Riebe; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AMPA; development; glutamate transmission; hippocampus; interneuron; NMDA; synapse;

    Sammanfattning : In the human brain there are about 100 billion excitatory glutamatergic neurons and 10 billion inhibitory GABAergic neurons. During development, these neurons are synaptically wired together into neural networks, functionally prepared to perform the full register of brain functions, and to learn from experiences. LÄS MER

  3. 8. Development and Characterization of a Global Brain Ischemia Model in the Mouse -A Genetic and Pharmacological Approach

    Författare :Tomas Olsson; Neuroinflammation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsykologi; Neurologi; neuropsychology; Neurology; global; hypothermia; hsp70; receptor; adenosine A1; NMDA; cystatin C; cell death; hippocampus; Brain; ischemia; neurophysiology;

    Sammanfattning : Brain ischemia is a major cause of death and morbidity in the industrialized countries. It is mainly caused by stroke, but may also be the consequence of successful cardiopulmonary resuscitation in victims of cardiac arrest, known as transient global ischemia. LÄS MER

  4. 9. Glutathione in the brain. Studies on efflux and possible implications in neurotoxicity

    Författare :Camilla Wallin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glutathione; excitotoxicity; hypoxia-ischemia; brain; rat; anoxia-aglycemia; g-glutamyl transpeptidase; glutamate; NMDA; oxidative stress; mitochondria; amino acids;

    Sammanfattning : Neuronal cell death in acute insults such as stroke, trauma and epilepsy involves overactivation of glutamate receptors, calcium influx and increased formation of potentially toxic reactive oxygen species. Glutathione is a key component in the antioxidant defense system against reactive oxygen species. LÄS MER

  5. 10. Spinal NMDA receptors and pain : experimental studies on behaviour, antinociception, spinal cord blood flow and neurotoxicity, pharmacokinetics and a clinical application

    Författare :Jens D. Kristensen; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER