Sökning: "NMDA receptors"
Visar resultat 11 - 15 av 102 avhandlingar innehållade orden NMDA receptors.
11. The role of excitatory amino acids in spinal sensory transmission : a behavioural and electrophysiological investigation with emphasis on NMDA receptors and nociception
Sammanfattning : .... LÄS MER
12. Developmental plasticity of the glutamate synapse: Roles of low frequency stimulation, hebbian induction and the NMDA receptor
Sammanfattning : The glutamate synapse is by far the most common synapse in the brain and acts via postsynaptic AMPA, NMDA and mGlu receptors. During brain development there is a continuous production of these synapses where those partaking in activity resulting in neuronal activity are subsequently selected to establish an appropriate functional pattern of synaptic connectivity while those that do not are elimimated. LÄS MER
13. Interactions between neuronal nicotinic acetylcholine receptors, N-methyl-aspartate receptors and beta-amyloid in the brain of genetically modified mice : implications for Alheimer's disease
Sammanfattning : The amyloid hypothesis is one of the leading theories in the search for the cause of Alzheimer's disease (AD) and is based on the theory that hyperproduction and accumulation of amyloid betapeptide (Abeta) in the brain triggers the disruption of neuronal and synaptic function, thereby ultimately leading to neurodegeneration and dementia. Some of the crucial questions are if Abeta has a neuronal function in the brain and how it interacts with the neurotransmitter system in AD. LÄS MER
14. Beyond AMPA and NMDA: Slow synaptic mGlu/TRPC currents : Implications for dendritic integration
Sammanfattning : In order to understand how the brain functions, under normal as well as pathological conditions, it is important to study the mechanisms underlying information integration. Depending on the nature of an input arriving at a synapse, different strategies may be used by the neuron to integrate and respond to the input. LÄS MER
15. Neuronal Cell Death and Restoration in the Basal Ganglia: Implications for Huntington's and Parkinson's diseases
Sammanfattning : Huntington's disease (HD) is a hereditary neurodegenerative disorder presenting with chorea, dementia and extensive striatal neuronal death. The mechanism through which the widely expressed mutant huntingtin mediates striatal neurotoxicity is unknown. Excitotoxicity, i.e. LÄS MER