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Visar resultat 1 - 5 av 102 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Spinal NMDA receptors and pain : experimental studies on behaviour, antinociception, spinal cord blood flow and neurotoxicity, pharmacokinetics and a clinical application

    Författare :Jens D. Kristensen; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 2. Neurosteroids Induce Allosteric Effects on the NMDA Receptor : Nanomolar Concentrations of Neurosteroids Exert Non-Genomic Effects on the NMDA Receptor Complex

    Författare :Tobias Johansson; Fred Nyberg; Pierre Le Grevès; Elisabeth Hansson; Uppsala universitet; []
    Nyckelord :Pharmaceutical pharmacology; Pharmacology; neurosteroids; NMDA receptor; NR2B subunit; ifenprodil; sigma receptor; anabolic androgenic steroids; allosteric modulation; non-genomic; Farmaceutisk farmakologi;

    Sammanfattning : The neurosteroids constitute a group of powerful hormones synthesized and acting in the central nervous system. They participate in a number of important central processes, such as memory and learning, mood and neuroprotection. LÄS MER

  4. 3. Chemical and stimulus-induced NMDA-dependent plasticity and the possible involved mechanisms

    Författare :Rui Li; Göteborgs universitet; []
    Nyckelord :synaptic plasticity; hippocampus; LTP; LTD; AMPA; NMDA; NR2A; NR2B;

    Sammanfattning : Long-term potentiation (LTP) and long-term depression (LTD) are considered as the most important forms of synaptic plasticity involved in learning and memory. The traditional way to induce LTP and LTD is by electric stimulation leading to activation of NMDA-R. LÄS MER

  5. 4. Plasticity and variation of synaptic responses in hippocampus. Role of AMPA and NMDA receptors

    Författare :Yin-Ping Niu; Göteborgs universitet; []
    Nyckelord :learning and memory; synaptic plasticity; hippocampus; synapse; AMPA receptor; NMDA receptor; LTP; LTD; CV; TFS;

    Sammanfattning : It is generally believed that synaptic plasticity in the central nervous system may underlie learning and memory as well as neuronal development. The most wellstudied examples of such synaptic plasticity are long-term potentiation (LTP) andlong-term depression (LTD). LÄS MER

  7. 5. Hypoxic-ischemic injury in the immature brain. Role of mitochondria, caspases and NMDA receptors

    Författare :Malgorzata Puka-Sundvall; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neonatal; immature rats; hypoxia-ischemia; brain damage; calcium; mitochondria; permeability transition; apoptosis; caspase-3; NMDA receptor; electron microscopy;

    Sammanfattning : .... LÄS MER