Sökning: "NLME modeling"
Hittade 5 avhandlingar innehållade orden NLME modeling.
1. Nonlinear Mixed Effects Modeling of Combination Therapies in Oncology
Sammanfattning : It has been shown that simultaneous administration of two or more anticancer agents can have a beneficial effect on cancer patients. This type of treatment is called combination therapy and is nowadays commonly used in the fight against cancer. LÄS MER
2. Kinetic Models in Life Science — Contributions to Methods and Applications
Sammanfattning : Kinetic models in life science combine mathematics and biology to answer questions from areas such as cell biology, physiology, biotechnology, and drug development. The idea of kinetic models is to represent a biological system by a number of biochemical reactions together with mathematical expressions for the reaction kinetics, i.e. LÄS MER
3. Mixed Effects Modeling of Deterministic and Stochastic Dynamical Systems - Methods and Applications in Drug Development
Sammanfattning : Mathematical models based on ordinary differential equations (ODEs) are commonly used for describing the evolution of a system over time. In drug development, pharmacokinetic (PK) and pharmacodynamic (PD) models are used to characterize the exposure and effect of drugs. LÄS MER
4. Statistical modeling and design in forestry : The case of single tree models
Sammanfattning : Forest quantification methods have evolved from a simple graphical approach to complex regression models with stochastic structural components. Currently, mixed effects models methodology is receiving attention in the forestry literature. LÄS MER
5. Quantitative Clinical Pharmacological Studies on Efavirenz and Atazanavir in the Treatment of HIV-1 Infection
Sammanfattning : There are 34 million people infected with the HIV-1 virus in the world today. Due to increased access to antiretroviral therapy, AIDS related death has dropped by 30% since 2005. LÄS MER