Sökning: "NKT lymphocyte"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden NKT lymphocyte.

1. 1. Natural killer T (NKT) lymphocytes regulate of intestinal tumor immunity

   Författare :Ying Wang; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NKT lymphocyte; intestinal tumor; CD1d; colrectal cancer; immunoregulation; α-gagactosylceramide;

   Sammanfattning : CD1d-restricted natural killer T (NKT) lymphocytes are known as potent early regulatory cells of immune responses, acting as a bridge between innate and adaptive immunity. While invariant NKT (iNKT) cells have a protective role in many tumor models, their ability to promote intestinal inflammation, known to enhance intestinal cancer, raised the question if they would be protective in intestinal tumor development. LÄS MER

3. 2. Factors regulating lymphocyte development and peripheral activation

   Författare :Anna Makowska; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; NKT cells; TFG beta; Treg; Immunologi; serologi;

   Sammanfattning : Peripheral tolerance is regulated by different types of regulatory T cells, including CD1-restricted T cells and CD4+CD25+ regulatory T (Treg) cells. This thesis has focused on the interactions between T cells and antigen presenting cells (APCs) and the immunregulatory function of TGF-b as two important factors regulating differentiation and activation of T cells in the periphery. LÄS MER

4. 3. Genetics and functions of innate-like lymphocyte subsets

   Författare :Julia Rolf; Göteborgs universitet; []
   Nyckelord :innate-like lymphocyte; CD1d; autoimmunity; genetic mapping; microarray; Salmonella infection;

   Sammanfattning : The immune system contains three different branches: innate immunity, adaptive immunity and innate-like lymphocytes that share properties both with the innate and adaptive immune cells. The innate-like lymphocytes have the capacity to rapidly become activated by invading pathogens and also to modulate immune responses and thereby inhibit or promote inflammation. LÄS MER

5. 4. The leukocyte complexity and mutational landscape of periampullary adenocarcinoma. Morphology matters

   Författare :Sebastian Lundgren; Tumörmikromiljö; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; periampullary adenocarcinoma; pancreatic cancer; immune microenviroment; prognosis; macrophages; natural killer cells; natural killer T cells; T cells; B cells;

   Sammanfattning : Background: Periampullary adenocarcinomas are a heterogenous group of tumours with poor prognosis that hasnot improved considerably the last decades. Tumour morphology, i.e. intestinal type (I-type) or pancreatobiliarytype (PB-type), has been demonstrated to be a more relevant prognostic factor than anatomical origin. LÄS MER

7. 5. Immunoregulation in experimental autoimmune myasthenia gravis

   Författare :Hua-Bing Wang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Myasthenia gravis (MG) derives its name from Latin and Greek words meaning, "grave muscle weakness". MG is a classical T cell dependent antibody-mediated autoimmune disease. LÄS MER