Sökning: "NK-cells"

Visar resultat 21 - 25 av 258 avhandlingar innehållade ordet NK-cells.

  1. 21. Peripheral immunity in patients with autoimmune endocrine diseases and the influence of physiological adaptions during pregnancy

    Författare :Louise Magnusson; Per-Ola Carlsson; Rosaura Casas; Ola Winqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Hashimoto´s thyroiditis; Graves´ disease; autoimmune Addison´s disease; antigen-presenting cells; B cells; non-classical monocytes; NK cells; memory CD8 T cells; CDCP1; SLAMF1; inflammation; lymphocyte activation; pregnancy; β-cell function; C-peptide; plasma proteome; prolactin; prokineticin-1; glucagon; oral glucose tolerance test; mass cytometry; proximity extension assay; Medicinsk vetenskap; Medical Science; Klinisk immunologi; Clinical Immunology; Endocrinology and Diabetology; Endokrinologi och Diabetologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Type 1 diabetes (T1D), Hashimoto’s thyroiditis (HT), Graves’ disease (GD), and autoimmune Addison’s disease (AD) appear to share immunogenetic mechanisms. This idea is not novel, as “autoimmune tautology” is an established concept. LÄS MER

  3. 22. The tumor immune microenvironment and clinical outcome in patients with esophageal and gastric adenocarcinoma

    Författare :Maria C Svensson; Personlig patologi och cancerbehandling; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin och hälsovetenskap; tumor immune microenironment; Esophageal cancer; Gastric cancer; prognosis; Prediction; Adenocarcinoma; T cells; B cells; NK cells; tumor-associated macrophage TAM ; PD-L1; PD-1;

    Sammanfattning : .... LÄS MER

  4. 23. Triggering and inhibitory molecules affecting target cell recognition by NK cells

    Författare :Margarita Salcedo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NK cell; MHC class 1; NKinhibitory receptors; costimulatory molecules ISBN 9 1-628-2643-3;

    Sammanfattning : NK cells were described originally for their ability to lyse certain tumor cell lines without prior immunization. MHC class I molecules have been shown to deliver a negative signal to NK cells preventing killing of target cells. This reaction is mediated via specific receptors on NK cells, referred to as KIR in man and Ly49 in mouse. LÄS MER

  5. 24. Activation of human dendritic cells : role of the allergenic yeast Malassezia and NK cells

    Författare :Eva Buentke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Antigen-presenting cells; atopic eczema dermatitis syndrome; cytokines; dendritic cells; Malassezia; NK cells; yeast;

    Sammanfattning : Immature bone marrow derived dendritic cells (DCs) patrol the periphery of our body, where they encounter and take up foreign antigens. Once activated, DCs migrate to regional lymph nodes to present peptides derived from these antigens to naive T cells, and elicit different T helper (Th) cell responses. LÄS MER

  7. 25. Regulation of Type I Interferon Production in Plasmacytoid Dendritic Cells : Effect of Genetic Factors and Interactions with NK Cells and B Cells

    Författare :Olof Berggren; Maija-Leena Eloranta; Niels Heegaard; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic lupus erythemtosus; IFN-alpha; autoimmunity; immune complex; single nuclear polymorphisms; Medicinsk vetenskap; Medical Science;

    Sammanfattning : The type I interferon (IFN) system plays a central role in the etiopathogenesis of many autoimmune diseases, e.g. systemic lupus erythematosus (SLE). Activation of the type I IFN system in SLE is promoted by endogenous nucleic acid-containing immune complexes (ICs) which stimulate plasmacytoid dendritic cells (pDCs). LÄS MER