Sökning: "NK-cells"
Visar resultat 16 - 20 av 258 avhandlingar innehållade ordet NK-cells.
16. The activation and regulation of plasmacytoid dendritic cells in SLE : and possible therapeutic interventions
Sammanfattning : Systemic Lupus Erythematosus (SLE) is an autoimmune disease, characterized by the presence of anti-nuclear antibodies and the formation of nucleic acid containing immune complexes (ICs), which can cause organ damage by deposition in tissues. ICs strongly trigger the plasmacytoid dendritic cells (pDCs) to produce interferon (IFN)-α, which potently activates the immune system. LÄS MER
17. Effects of Complement Opsonization of HIV on Dendritic Cells : and Implications for the Immune Response
Sammanfattning : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. LÄS MER
18. Microbial and maternal influences on allergic sensitization during childhood: defining a role for monocytes
Sammanfattning : Allergic diseases are influenced by genetics and the environment. Maternal allergy appears to confer a higher risk for allergic sensitization than paternal allergy, suggesting an in utero influence. LÄS MER
19. Innate and acquired immunity to herpes simplex virus type 2 glycoprotein G in humans
Sammanfattning : Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the human genital tract mucosa and is the most common cause of genital ulcer disease in humans. The infection exhibits a broad clinical spectrum, ranging from severe recurrent episodes of genital herpes to being completely asymptomatic. LÄS MER
20. Targeting NOX2 in cancer
Sammanfattning : Reactive oxygen species (ROS) are short-lived, toxic derivatives of oxygen that are produced during mitochondrial respiration and by NADPH oxidases (NOX). By enzymatically generating ROS, the myeloid cell NOX2 plays a critical role in defense against bacteria and other microorganisms. LÄS MER