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1. 1. Modulation of the HPA axis alters the sensitivity of the cochlea to acoustic trauma

   Författare :Yeasmin Tahera; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :HPA axis; corticosterone; glucocorticoid receptor; NFêB; spiral ganglion neurons; cochlea; acoustic trauma; paraventricular nucleus;

   Sammanfattning : The hypothalamic pituitary adrenal axis (HPA axis) regulates nearly all neuroendocrine responses of the body. An active HPA axis is crucial to maintaining homeostasis. An altered reactivity of the HPA axis can affect several physiological systems including the auditory system. LÄS MER