Sökning: "NDST1"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet NDST1.

  1. 1. Role of Heparan Sulfate N-sulfation in Mouse Embryonic Development

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anders Dagälv; Uppsala universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; heparan sullfate; heparin; proteoglycan; NDST1; NDST2; coreprotein; syndecan; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; Biokemi; Biochemistry;

    Sammanfattning : Heparan sulfate (HS) is a sulfated glycosaminoglycan expressed by all cells in the body. It is found at the cell surface and in the extracellular matrix where it binds a large amount of various ligands including growth factors and morphogens. LÄS MER

  2. 2. Heparan Sulfate Proteoglycans in Brain Tumor Development

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Argyris Spyrou; Uppsala universitet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; pediatric brain tumors; heparanase; NDST1; heparan sulfate proteoglycans; CD24; glycosaminoglycan mimetics; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Sammanfattning : Malignant brain tumors are aggressive neoplasms that remain challenging to treat in spite of their detailed molecular characterization. Both adults and children may suffer from brain tumors, which, if not lethal, can cause severe long-term and devastating side effects. LÄS MER

  3. 3. Heparan Sulfate and Development A Study of NDST Deficient Mice and Embryonic Stem Cells

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Katarina Holmborn; Uppsala universitet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell and molecular biology; heparan sulfate; proteoglycan; biosynthesis; N-deacetylase N-sulfotransferase; NDST; gene targeting; embryonic development; lung development; mast cells; Cell- och molekylärbiologi;

    Sammanfattning : Heparan sulfate (HS) proteoglycans consist of sulfated HS chains covalently bound to core proteins. They are ubiquitously expressed, on the cell surface and in the extracellular matrix, throughout the body. LÄS MER

  4. 4. N-Sulfation and Polymerization in Heparan Sulfate Biosynthesis

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jenny Presto; Uppsala universitet.; [2006]
    Nyckelord :Cell and molecular biology; Heparan sulfate; N-deacetylase N-sulfotransferase; NDST; EXT1; EXT2; Biosynthesis; Cell- och molekylärbiologi;

    Sammanfattning : Heparan sulfate (HS) is a glycosaminoglycan present in all cell types covalently attached to core proteins forming proteoglycans. HS interacts with different proteins and thereby affects a variety of processes. LÄS MER

  5. 5. Functions of Heparan Sulfate During Mouse Development Studies of Mice with Genetically Altered Heparan Sulfate Biosynthesis

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Maria Ringvall; Uppsala universitet.; [2004]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; embryonic development; gene targeting; lung development; ossification; heparan sulfate; heparin; N-deacetylase N-sulfaotransferase; NDST; proteoglycan; morphogen; biosynthesis; Utvecklingsbiologi; NATURAL SCIENCES Biology Organism biology Developmental biology; NATURVETENSKAP Biologi Organismbiologi Utvecklingsbiologi;

    Sammanfattning : Heparan sulfate (HS) is a ubiquitous polysaccharide on the cell surface and in the extracellular matrix. HS is an important actor in the regulation of cell signaling, especially in the developing embryo. LÄS MER