Sökning: "NC100150 Injection"

Hittade 4 avhandlingar innehållade orden NC100150 Injection.

1. 1. Proton Relaxation Properties of a Particulate Iron Oxide MR Contrast Agent in Different Tissue Systems : Implications for Imaging

   Författare :Atle Bjørnerud; Graham A. Wright; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Iron oxide nanoparticles; USPIO; NC100150 Injection; water exchange limited relaxation; MR perfusion imaging.; Onkologi; Oncology; Onkologi; radiologi; Radiology;

   Sammanfattning : Knowledge of the relationship between in vivo contrast agent concentration and magnetic resonance (MR) signal response is an important requirement in contrast enhanced MR imaging in general and in MR based perfusion imaging in particular. This relationship is a complex function of the properties of the contrast agent as well as the structure of the target tissue. LÄS MER

3. 2. The Utility of Ultrasmall Superparamagnetic Iron Oxide Contrast Agents for Cardiovascular Magnetic Resonance Imaging

   Författare :Lars Johansson; Håkan Ahlström; Hans-Jørgen Smith; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiology; Magnetic resonance imaging; Contrast agent; Iron Oxide; Cardiovascular; Radiologisk forskning; Radiological research; Radiologisk forskning;

   Sammanfattning : The purpose of this thesis was to investigate the utility of the Ultrasmall Superparamagnetic Iron Oxide Particle (USPIO), NC100150 Injection for assessment of macro- and microvascular morphology and function using magnetic resonance imaging. The feasibility of NC100150 Injection was tested for the following applications: Coronary angiography, Thrombus detection, Cardiac function, Myocardial perfusion, Assessment of myocardial blood volume and water exchange and finally assessment of endothelial integrity of the myocardium. LÄS MER

4. 3. Assessment of Myocardial Perfusion with Magnetic Resonance Imaging and an Intravascular Contrast Agent

   Författare :Tomas Bjerner; Christine Lorenz; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Magnetic resonance imaging; Intravascular contrast agents; Myocardial perfusion; Onkologi; Oncology; Onkologi; radiologi; Radiology;

   Sammanfattning : The intravascular contrast agent NC100150 Injection (Clariscan™) was tested for its ability to induce signal intensity changes in myocardium, both in steady state and during first pass, and thereby demarcating non-perfused myocardium from perfused. Steady state: Ex vivo in pigs and when using 4 mg Fe/kg bodyweight (b.w. LÄS MER

5. 4. On contrast-enhanced magnetic resonance angiography of the aortoiliac arteries

   Författare :Johan Wikström; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Magnetic resonance imaging; Magnetic resonance angiography; Contrast media; Arteriosclerosis; Iliac artery; Blood pressures; Onkologi; Oncology; Onkologi; radiologi; Radiology;

   Sammanfattning : In contrast-enhanced magnetic resonance angiography (CE-MRA),vascular signal is produced by the acquisition of a T1-weighted magnetic resonance imaging scan while the presence of a contrast agent induces a low T1 in blood. In this thesis,CE-MRA of the aortoiliac arteries was evaluated. LÄS MER