Sökning: "NATURVETENSKAP Kemi Biokemi Strukturbiologi"

Visar resultat 6 - 10 av 44 avhandlingar innehållade orden NATURVETENSKAP Kemi Biokemi Strukturbiologi.

  1. 6. Generation and exploitation of proton motive force: Biochemical and structural analysis of three bacterial integral membrane proteins

    Författare :Pontus Emanuel Gourdon; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; X-ray crystallography; AcrB; structure; proteorhodopsin; multi-drug resistance; transhydrogenase; membrane proteins; proton motive force;

    Sammanfattning : Proton motive force, a necessity for all living cells, is generated and exploited by asignificant number of membrane-bound enzymes and transporters. The focus of thisthesis was to understand the physiological relevance, structure and mechanism of threesuch bacterial enzymes: proteorhodopsin; transhydrogenase; and AcrB. LÄS MER

  3. 7. On the crystallization of membrane proteins in lipidic sponge and cubic phases

    Författare :Pia Jeanette Hindrichsen; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; monoolein MO ; selachyl alcohol; cubic phase; sponge phase; small angle X-ray scattering; protein crystallization; phytantriol PT ;

    Sammanfattning : Membrane proteins are involved in many important biological processes and in order to understand their mechanism, their three-dimensional structures need to be elucidated to high resolution by for example X-ray crystallography. However, there is only limited structural knowledge for membrane proteins which is partly explained by the difficulties in obtaining well-diffracting crystals. LÄS MER

  4. 8. Housing Aquaporins in Nanostructured Glass

    Författare :Simon Isaksson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Membrane protein; Water; Interface; Aquaporin; Silica; Formation; Silicification;

    Sammanfattning : Proteins are a group of biomolecules that perform versatile tasks, which in many cases are essential for life. The magnitude of their importance is perhaps expressed by the word protein itself, coined by the Swedish chemist Jöns Jacob Berzelius in the summer of 1838. LÄS MER

  5. 9. Calculations of Reaction Mechanisms and Entropic Effects in Enzyme Catalysis

    Författare :Masoud Kazemi; Johan Åqvist; Per E. M. Siegbahn; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Enzyme catalysis; Entropy; Cytidine deamination; Ribosome; Peptidyl-tRNA hydrolysis; Peptide bond formation; Empirical valence bond method; Density functional theory; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi; Biokemi; Biochemistry; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : Ground state destabilization is a hypothesis to explain enzyme catalysis. The most popular interpretation of it is the entropic effect, which states that enzymes accelerate biochemical reactions by bringing the reactants to a favorable position and orientation and the entropy cost of this is compensated by enthalpy of binding. LÄS MER

  7. 10. Light’EM up! : structural characterization of light-driven membrane protein complexes by cryogenic electron microscopy

    Författare :André Tomás Graça; Wolfgang P. Schröder; Johannes Messinger; Karina Persson; Werner Kühlbrandt; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 3D reconstruction; Arabidopsis thaliana; assembly; chlorophyll; cryo-EM; cyanobacteria; Deinococus radiodurans; electron; land plants; membrane protein complexes; Photosystem II; proton; single-particle analysis; S-Layer Deinoxanthin Binding Complex SDBC ; water.; Biochemistry; biokemi; biologisk kemi; biological chemistry;

    Sammanfattning : Photosynthesis is probably the most important process for allowing life to develop into the diverse forms we see today. In this process, solar radiation is used to convert CO2 into biomass. From this process, we obtain oxygen to breathe, sources of food (plant biomass), and the potential for clean and sustainable energy. LÄS MER