Sökning: "NATURVETENSKAP Biologi Övrig biologi Bioinformatik"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden NATURVETENSKAP Biologi Övrig biologi Bioinformatik.

  1. 1. On Transcriptome Sequencing

    Detta är en avhandling från Stockholm : KTH

    Författare :Daniel Klevebring; Joakim Lundeberg; Ulf Gyllensten; [2009]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transcriptome; RNA-seq; DNA sequencing; gene expression profiling; non-coding RNA; small RNA; NATURAL SCIENCES Biology Other biology Functional genomics; NATURVETENSKAP Biologi Övrig biologi Funktionsgenomik; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik; NATURAL SCIENCES Biology Cell and molecular biology Genetics; NATURVETENSKAP Biologi Cell- och molekylärbiologi Genetik; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi;

    Sammanfattning : This thesis is about the use of massive DNA sequencing to investigate the transcriptome. During recent decades, several studies have made it clear that the transcriptome comprises a more complex set of biochemical machinery than was previously believed. LÄS MER

  2. 2. Prediction, modeling, and refinement of protein structure

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Per Larsson; Arne Elofsson; Erik Lindahl; Barry Honig; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein structure prediction; Multiple alignments; Quality assessment; Molecular dynamics; Implicit solvent; Refinement; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik; NATURAL SCIENCES Chemistry Theoretical chemistry Bioinformatics; NATURVETENSKAP Kemi Teoretisk kemi Bioinformatik; NATURAL SCIENCES Chemistry Theoretical chemistry Statistical mechanics; NATURVETENSKAP Kemi Teoretisk kemi Statistisk mekanik; Biochemistry; biokemi;

    Sammanfattning : Accurate predictions of protein structure are important for understanding many processes in cells. The interactions that govern protein folding and structure are complex, and still far from completely understood. However, progress is being made in many areas. Here, efforts to improve the overall quality of protein structure models are described. LÄS MER

  3. 3. The Nucleosome as a Signal Carrying Unit From Experimental Data to Combinatorial Models of Transcriptional Control

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Stefan Enroth; Jan Komorowski; Claes Wadelius; Rickard Sandberg; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Next generation sequencing; Nucleosome; Histone modification; Transcriptional regulation; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik; TECHNOLOGY Bioengineering Bioinformatics; TEKNIKVETENSKAP Bioteknik Bioinformatik; Bioinformatik; Bioinformatics;

    Sammanfattning : The human genome consists of over 3 billion nucleotides and would be around 2 meters long if uncoiled and laid out. Each human somatic cell contains all this in their nucleus which is only around 5 µm across. This extreme compaction is largely achieved by wrapping the DNA around a histone octamer, the nucleosome. LÄS MER

  4. 4. Characterization and Evolution of Transmembrane Proteins with Focus on G-protein coupled receptors in Pre-vertebrate Species

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Karl J. V. Nordström; Helgi B. Schiöth; Robert Fredriksson; Teresa Attwood; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; G protein-coupled receptors; GPCR; Membrane protein; Rhodopsin; Adhesion; Secretin; Evolution; Bioinformatics; Phylogeny; MEDICINE Physiology and pharmacology Pharmacological research; MEDICIN Fysiologi och farmakologi Farmakologisk forskning; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik; Bioinformatik; Bioinformatics; Biology with specialization in Molecular Evolution; Biologi med inriktning mot molekylär evolution;

    Sammanfattning : G protein-coupled receptors (GPCRs) are one of the largest protein families in mammals. GPCRs are instrumental for hormonal and neurotransmitter signalling and are important in all major physiological systems of the body. LÄS MER

  5. 5. Decoding the Structural Layer of Transcriptional Regulation Computational Analyses of Chromatin and Chromosomal Aberrations

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Robin Andersson; Jan Komorowski; Jan Dumanski; Claes Wadelius; Anders Krogh; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chromatin; Nucleosome positioning; Histone modifications; Chromosomal aberrations; Transcriptional regulation; Array-CGH; Next generation sequencing; ChIP-chip; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik; Bioinformatics; Bioinformatik;

    Sammanfattning : Gene activity is regulated at two separate layers. Through structural and chemical properties of DNA – the primary layer of encoding – local signatures may enable, or disable, the binding of proteins or complexes of them with regulatory potential to the DNA. LÄS MER