Sökning: "NATURAL SCIENCES Chemistry Theoretical chemistry Bioinformatics"
Visar resultat 6 - 10 av 14 avhandlingar innehållade orden NATURAL SCIENCES Chemistry Theoretical chemistry Bioinformatics.
6. Structural dynamics of ribulose-1,5-bisphosphate carboxylase/oxygenase
Sammanfattning : Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) assimilates carbon dioxide (CO2) from air into biomass. Due to its slow turnover, the reaction is a rate-limiting step in photosynthetic carbon fixation. LÄS MER
7. Topology Prediction of Membrane Proteins: Why, How and When?
Sammanfattning : Membrane proteins are of broad interest since they constitute a large fraction of the proteome in all organisms, up to 20-30%. They play a crucial role in many cellular processes mediating information flow and molecular transport across otherwise nearly impermeable membranes. LÄS MER
8. The impact of GPCR structures on understanding receptor function and ligand binding
Sammanfattning : G protein-coupled receptors (GPCRs) form the largest superfamily of eukaryotic membrane proteins and are responsible for the action of nearly 30% of all marketed drugs. For a long period, efforts to study these receptors were limited by the paucity of atomic-resolution structural information. LÄS MER
9. Ensemble methods for protein structure prediction
Sammanfattning : Proteins play an essential role in virtually all of life's processes. Their function is tightly coupled to the three-dimensional structure they adopt.Solving protein structures experimentally is a complicated, time- and resource-consuming endeavor. LÄS MER
10. Network and gene expression analyses for understanding protein function
Sammanfattning : Biological function is the result of a complex network of functional associations between genes or their products. Modeling the dynamics underlying biological networks is one of the big challenges in bioinformatics. LÄS MER