Sökning: "NAFLD"

Visar resultat 6 - 10 av 34 avhandlingar innehållade ordet NAFLD.

  1. 6. Susceptibility to chronic liver disease

    Författare :Maria Antonella Burza; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic liver disease; susceptibility; human genetics; NAFLD; ALD; PNPLA3;

    Sammanfattning : The onset and the progression of chronic liver disease involve environmental and genetic factors. Hepatic stellate cells (HSCs) are important players in these processes and are the main storage site for retinol. LÄS MER

  3. 7. Metabolic and endocrine effects of SGLT2 inhibition

    Författare :Per Lundkvist; Jan Eriksson; Lars Lind; Maria J Pereira; Michael Alvarsson; Uppsala universitet; []
    Nyckelord :SGLT2 inhibition; GLP-1 receptor agonism; DPP4 inhibition; NAFLD; prediabetes; type 2 diabetes; obesity; metabolic syndrome; glucagon.; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Obesity and type 2 diabetes (T2D) are two growing global health problems with similar comorbidity profiles. SGLT2 inhibitors (SGLT2i) improve blood glucose control and can relieve both T2D and obesity, as well as their associated health problems such as hypertension, kidney failure, and cardiovascular disease. LÄS MER

  4. 8. Microbial modulation of metabolic diseases

    Författare :Antonio Molinaro; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiota; Glucose Metabolism; type 2 diabetes; NAFLD; non-alcoholic fatty liver disease;

    Sammanfattning : The gut microbiota, the ensemble of microorganisms living in the gastrointestinal tract, and the host have a mutualist relationship. Alterations of this delicate equilibrium can lead to changes in microbiota composition and/or function leading to the onset of metabolic diseases (e.g., type 2 diabetes and non-alcoholic fatty liver diseases). LÄS MER

  5. 9. From fatty liver to end-stage liver disease through type 2 diabetes

    Författare :Karl Björkström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The past decades have seen a marked increase in the incidence of type 2 diabetes and nonalcoholic fatty liver disease (NAFLD). Epidemiological studies have clearly demonstrated that there is an association between type 2 diabetes and NAFLD. LÄS MER

  7. 10. Aspects of diagnosis, prognosis and treatment of nonalcoholic fatty liver disease

    Författare :Magnus Holmer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease globally. NAFLD is caused by obesity, often in combination with type 2 diabetes mellitus (T2D). Lifestyle modifications that lead to weight loss, primarily diet change, is the only treatment proven to reverse steatosis and nonalcoholic steatohepatitis (NASH). LÄS MER