Avancerad sökning

Visar resultat 1 - 5 av 34 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Liver-related complications and metabolic comorbidities during long-term follow-up of patients with Non-Alcoholic Fatty Liver Disease

    Författare :Kristina Önnerhag; Gastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic kidney disease CKD ; Epidemiology; Fibrosis; Hepatocellular cancer; Insulin resistance; Liver cirrhosis; Metabolic syndrome; NAFLD; NASH; Non-alcoholic fatty liver disease; non-alcoholic steatohepatitis;

    Sammanfattning : Background: Non-alcoholic fatty liver disease (NAFLD) is highly associated with the metabolic syndrome, and due to increasing prevalence of for example obesity it is now the most common liver disease in the world. A minority progress to advanced fibrosis/cirrhosis, which is associated with increased mortality, but it is not entirely clear which patients who have an increased risk of fibrosis. LÄS MER

  3. 2. Role of Fatty Acid Composition in Non-Alcoholic Fatty Liver Disease: a Dietary Perspective : Results from Interventional and Observational Studies

    Författare :Michael Fridén; Ulf Risérus; Fredrik Rosqvist; Helen Lindqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fatty acids; Diet; Biomarkers; NAFLD; Liver fat; Fibrosis; Cirrhosis; HCC; Nutrition; Nutrition;

    Sammanfattning : The overall aim of this doctoral thesis was to investigate the role of circulating, liver and dietary fatty acids in non-alcoholic fatty liver disease (NAFLD). For circulating and liver fatty acids, special emphasis was given to fatty acids reflecting diet. LÄS MER

  4. 3. Genetic variants for liver fat accumulation and circulating triglyceride levels

    Författare :Ivana Stojkovic; Diabetes - kardiovaskulär sjukdom; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NAFLD; genetic variations; triglycerides; ALAT; dietary intake; type 2 diabetes; cardiovascular disease;

    Sammanfattning : Non-alcoholic fatty liver disease (NAFLD), obesity and type 2 diabetes(T2D) are strongly associated and today their prevalence reaches epidemic proportions. NAFLD has a multi-factorial aetiology, both genetic and environmental factors are equally important. LÄS MER

  5. 4. The role of MBOAT7 on fatty liver disease

    Författare :Andrea Caddeo; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver disease; medicine; Genetics; NAFLD;

    Sammanfattning : Non-alcoholic fatty liver disease (NAFLD) is the main health disorder in internal medicine, affecting one third of the population worldwide. Environmental and genetic factors contribute to NAFLD susceptibility and progression. LÄS MER

  7. 5. Protein kinase STK25 is a regulator of hepatic lipid partitioning and whole body metabolism

    Författare :Manoj Amrutkar; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NAFLD; NASH; Liver lipid metabolism; Type 2 diabetes; STK25;

    Sammanfattning : In past decade, type 2 diabetes (T2D) and associated metabolic complications have become a major global threat for human health with epidemic increase in incidence. Currently available treatments for T2D have several limitations and side effects making it difficult safely reach adequate metabolic control. LÄS MER